Alternative splicing of the Menkes copper Atpase (Atp7a) transcript in the rat intestinal epithelium
about
Regulation of brain iron and copper homeostasis by brain barrier systems: implication in neurodegenerative diseasesTranscriptional regulation of the Menkes copper ATPase (Atp7a) gene by hypoxia-inducible factor (HIF2{alpha}) in intestinal epithelial cellsSilencing the Menkes copper-transporting ATPase (Atp7a) gene in rat intestinal epithelial (IEC-6) cells increases iron flux via transcriptional induction of ferroportin 1 (Fpn1)Copper stabilizes the Menkes copper-transporting ATPase (Atp7a) protein expressed in rat intestinal epithelial cellsTranscription factors Sp1 and Hif2α mediate induction of the copper-transporting ATPase (Atp7a) gene in intestinal epithelial cells during hypoxiaSilencing of the Menkes copper-transporting ATPase (Atp7a) gene increases cyclin D1 protein expression and impairs proliferation of rat intestinal epithelial (IEC-6) cells.Cross-species comparison of genomewide gene expression profiles reveals induction of hypoxia-inducible factor-responsive genes in iron-deprived intestinal epithelial cells.Investigation of iron metabolism in mice expressing a mutant Menke's copper transporting ATPase (Atp7a) protein with diminished activity (Brindled; Mo (Br) (/y) ).Serum ceruloplasmin protein expression and activity increases in iron-deficient rats and is further enhanced by higher dietary copper intake.Exploration of the copper-related compensatory response in the Belgrade rat model of genetic iron deficiencyMultiple Menkes copper ATPase (Atp7a) transcript and protein variants are induced by iron deficiency in rat duodenal enterocytesMetabolic crossroads of iron and copper.Metal-Dependent Regulation of ATP7A and ATP7B in Fibroblast Cultures.Human macrophage ATP7A is localized in the trans-Golgi apparatus, controls intracellular copper levels, and mediates macrophage responses to dermal wounds.Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia-inducible factor 2α.Loss of divalent metal transporter 1 function promotes brain copper accumulation and increases impulsivity.Counteract of bone marrow of blotchy mice against the increases of plasma copper levels induced by high-fat diets in LDLR-/- mice.
P2860
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P2860
Alternative splicing of the Menkes copper Atpase (Atp7a) transcript in the rat intestinal epithelium
description
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
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scientific journal article
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vedecký článok (publikovaný 2009/10/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/10/01)
@nl
наукова стаття, опублікована в жовтні 2009
@uk
مقالة علمية (نشرت في أكتوبر 2009)
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name
Alternative splicing of the Me ...... the rat intestinal epithelium
@ast
Alternative splicing of the Me ...... the rat intestinal epithelium
@en
Alternative splicing of the Me ...... the rat intestinal epithelium
@nl
type
label
Alternative splicing of the Me ...... the rat intestinal epithelium
@ast
Alternative splicing of the Me ...... the rat intestinal epithelium
@en
Alternative splicing of the Me ...... the rat intestinal epithelium
@nl
prefLabel
Alternative splicing of the Me ...... the rat intestinal epithelium
@ast
Alternative splicing of the Me ...... the rat intestinal epithelium
@en
Alternative splicing of the Me ...... the rat intestinal epithelium
@nl
P2093
P2860
P3181
P356
P1476
Alternative splicing of the Me ...... the rat intestinal epithelium
@en
P2093
James F. Collins
P. N. Ranganathan
P2860
P304
P3181
P356
10.1152/AJPGI.00203.2009
P577
2009-10-01T00:00:00Z