Exploration of the copper-related compensatory response in the Belgrade rat model of genetic iron deficiency
about
Charting the travels of copper in eukaryotes from yeast to mammalsCopper stabilizes the Menkes copper-transporting ATPase (Atp7a) protein expressed in rat intestinal epithelial cellsTranscription factors Sp1 and Hif2α mediate induction of the copper-transporting ATPase (Atp7a) gene in intestinal epithelial cells during hypoxiaRegulation of DMT1 on Bone Microstructure in Type 2 Diabetes.Discovery of a cytosolic/soluble ferroxidase in rodent enterocytes.Impairment of interrelated iron- and copper homeostatic mechanisms in brain contributes to the pathogenesis of neurodegenerative disorders.Immunoreactive hephaestin and ferroxidase activity are present in the cytosolic fraction of rat enterocytes.Multiple Menkes copper ATPase (Atp7a) transcript and protein variants are induced by iron deficiency in rat duodenal enterocytesWhole-genome sequencing identifies a novel ABCB7 gene mutation for X-linked congenital cerebellar ataxia in a large family of Mongolian ancestry.Divalent metal transporter 1 (Dmt1) mediates copper transport in the duodenum of iron-deficient rats and when overexpressed in iron-deprived HEK-293 cells.Pathophysiology of the Belgrade rat.Loss of divalent metal transporter 1 function promotes brain copper accumulation and increases impulsivity.Counteract of bone marrow of blotchy mice against the increases of plasma copper levels induced by high-fat diets in LDLR-/- mice.
P2860
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P2860
Exploration of the copper-related compensatory response in the Belgrade rat model of genetic iron deficiency
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Exploration of the copper-rela ...... del of genetic iron deficiency
@ast
Exploration of the copper-rela ...... del of genetic iron deficiency
@en
type
label
Exploration of the copper-rela ...... del of genetic iron deficiency
@ast
Exploration of the copper-rela ...... del of genetic iron deficiency
@en
prefLabel
Exploration of the copper-rela ...... del of genetic iron deficiency
@ast
Exploration of the copper-rela ...... del of genetic iron deficiency
@en
P2093
P2860
P356
P1476
Exploration of the copper-rela ...... del of genetic iron deficiency
@en
P2093
Changae Kim
James F Collins
Lingli Jiang
Perungavur Ranganathan
P2860
P304
P356
10.1152/AJPGI.00261.2011
P577
2011-08-18T00:00:00Z