Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5
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Protein phosphatase 5 protects neurons against amyloid-beta toxicityJNK Signaling: Regulation and Functions Based on Complex Protein-Protein PartnershipsAutophagy in Neurodegenerative Diseases and Metal NeurotoxicityImpacts of environmental toxicants on male reproductive dysfunctionReactive oxygen species, cellular redox systems, and apoptosisCaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell deathCadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell deathBlood cadmium levels and Alzheimer's disease mortality risk in older US adultsCadmium-Induced Pathologies: Where Is the Oxidative Balance Lost (or Not)?GRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells.Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's diseaseN-acetyl-L-cysteine protects against cadmium-induced neuronal apoptosis by inhibiting ROS-dependent activation of Akt/mTOR pathway in mouse brain.Pattern-specific sustained activation of tyrosine hydroxylase by intermittent hypoxia: role of reactive oxygen species-dependent downregulation of protein phosphatase 2A and upregulation of protein kinasesOxidants positively or negatively regulate nuclear factor kappaB in a context-dependent mannerThe contribution of reactive oxygen species and p38 mitogen-activated protein kinase to myofilament oxidation and progression of heart failure in rabbits.Effects of cadmium chloride on the cultured human lens epithelial cells.Cadmium induces neuronal cell death through reactive oxygen species activated by GADD153.Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.Cadmium-induced apoptosis in primary rat cerebral cortical neurons culture is mediated by a calcium signaling pathway.Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network.Role of oxidative stress in cadmium toxicity and carcinogenesis.Protective effect of Irvingia gabonensis stem bark extract on cadmium-induced nephrotoxicity in rats.Cadmium exposure activates the ERK signaling pathway leading to altered osteoblast gene expression and apoptotic death in Saos-2 cells.The Ambiguous Relationship of Oxidative Stress, Tau Hyperphosphorylation, and Autophagy Dysfunction in Alzheimer's Disease.Requirement of ERα and basal activities of EGFR and Src kinase in Cd-induced activation of MAPK/ERK pathway in human breast cancer MCF-7 cells.Curcumin inhibits protein phosphatases 2A and 5, leading to activation of mitogen-activated protein kinases and death in tumor cells.Ectopic expression of human MutS homologue 2 on renal carcinoma cells is induced by oxidative stress with interleukin-18 promotion via p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal kinase (JNK) signaling pathways.Cadmium induces apoptosis in primary rat osteoblasts through caspase and mitogen-activated protein kinase pathways.Transcriptome Profiling Analysis of Wolf Spider Pardosa pseudoannulata (Araneae: Lycosidae) after Cadmium Exposure.Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway.Rapamycin inhibits Erk1/2-mediated neuronal apoptosis caused by cadmium.Fusarochromanone-induced reactive oxygen species results in activation of JNK cascade and cell death by inhibiting protein phosphatases 2A and 5.Akt attenuates apoptotic death through phosphorylation of H2A under hydrogen peroxide-induced oxidative stress in PC12 cells and hippocampal neurons.Oxidative stress and mitogen-activated protein kinase pathways involved in cadmium-induced BRL 3A cell apoptosis.Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding site.N-acetylcysteine protects against cadmium-induced germ cell apoptosis by inhibiting endoplasmic reticulum stress in testes.Cadmium and its neurotoxic effectsEmptying of Intracellular Calcium Pool and Oxidative Stress Imbalance Are Associated with the Glyphosate-Induced Proliferation in Human Skin Keratinocytes HaCaT CellsLow level methylmercury enhances CNTF-evoked STAT3 signaling and glial differentiation in cultured cortical progenitor cells
P2860
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P2860
Cadmium activates the mitogen-activated protein kinase (MAPK) pathway via induction of reactive oxygen species and inhibition of protein phosphatases 2A and 5
description
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Juli 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/10/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/10/01)
@nl
наукова стаття, опублікована в жовтні 2008
@uk
مقالة علمية (نشرت في أكتوبر 2008)
@ar
name
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@ast
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@en
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@nl
type
label
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@ast
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@en
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@nl
prefLabel
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@ast
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@en
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@nl
P3181
P1476
Cadmium activates the mitogen- ...... protein phosphatases 2A and 5
@en
P2093
P304
P3181
P356
10.1016/J.FREERADBIOMED.2008.07.011
P577
2008-07-26T00:00:00Z