Distinct domains of tRNA synthetase recognize the same base pair
about
Exome sequencing identifies mitochondrial alanyl-tRNA synthetase mutations in infantile mitochondrial cardiomyopathyPrediction and classification of aminoacyl tRNA synthetases using PROSITE domainsThe structure of alanyl-tRNA synthetase with editing domainUnique protein architecture of alanyl-tRNA synthetase for aminoacylation, editing, and dimerizationThe C-Ala Domain Brings Together Editing and Aminoacylation Functions on One tRNAParadox of mistranslation of serine for alanine caused by AlaRS recognition dilemmap23H implicated as cis/trans regulator of AlaXp-directed editing for mammalian cell homeostasisEvolution of RNA-protein interactions: non-specific binding led to RNA splicing activity of fungal mitochondrial tyrosyl-tRNA synthetasesThe Mitochondrial Aminoacyl tRNA Synthetases: Genes and Syndromes.Computational analysis of tRNA identity.Do anticodons of misacylated tRNAs preferentially mismatch codons coding for the misloaded amino acid?A major determinant for binding and aminoacylation of tRNA(Ala) in cytoplasmic Alanyl-tRNA synthetase is mutated in dominant axonal Charcot-Marie-Tooth diseaseIntroduction of a leucine half-zipper engenders multiple high-quality crystals of a recalcitrant tRNA synthetaseResampling and editing of mischarged tRNA prior to translation elongation.Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetaseAn assessment of mechanisms underlying peripheral axonal degeneration caused by aminoacyl-tRNA synthetase mutations.Mistranslation and its control by tRNA synthetases.Substrate-mediated fidelity mechanism ensures accurate decoding of proline codons.Ancestral AlaX editing enzymes for control of genetic code fidelity are not tRNA-specific.Structural analyses clarify the complex control of mistranslation by tRNA synthetasesExclusive use of trans-editing domains prevents proline mistranslationDevelopment of tRNA synthetases and connection to genetic code and disease.An editing activity that prevents mistranslation and connection to disease.tRNAs: cellular barcodes for amino acids.Distinct tRNA recognition strategies used by a homologous family of editing domains prevent mistranslation.Transfer RNA: a dancer between charging and mis-charging for protein biosynthesis.Discharging tRNAs: a tug of war between translation and detoxification in Escherichia coli.The phenotypic expression of mitochondrial tRNA-mutations can be modulated by either mitochondrial leucyl-tRNA synthetase or the C-terminal domain thereof.Role of D-aminoacyl-tRNA deacylase beyond chiral proofreading as a cellular defense against glycine mischarging by AlaRS.Substrate specificity and catalysis by the editing active site of Alanyl-tRNA synthetase from Escherichia coli.Natural homolog of tRNA synthetase editing domain rescues conditional lethality caused by mistranslation.The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis.Guanidine hydrochloride mediated denaturation of E. coli Alanyl-tRNA synthetase: identification of an inactive dimeric intermediate.Structural and functional consequences of mutating a proteobacteria-specific surface residue in the catalytic domain of Escherichia coli GluRS.A discriminator code-based DTD surveillance ensures faithful glycine delivery for protein biosynthesis in bacteriaDistinct ways of G:U recognition by conserved tRNA binding motifsANKRD16 prevents neuron loss caused by an editing-defective tRNA synthetase
P2860
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P2860
Distinct domains of tRNA synthetase recognize the same base pair
description
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2008
@ast
scientific journal article
@en
vedecký článok (publikovaný 2008/01/03)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/01/03)
@nl
наукова стаття, опублікована в січні 2008
@uk
مقالة علمية (نشرت في 3-1-2008)
@ar
name
Distinct domains of tRNA synthetase recognize the same base pair
@ast
Distinct domains of tRNA synthetase recognize the same base pair
@en
Distinct domains of tRNA synthetase recognize the same base pair
@nl
type
label
Distinct domains of tRNA synthetase recognize the same base pair
@ast
Distinct domains of tRNA synthetase recognize the same base pair
@en
Distinct domains of tRNA synthetase recognize the same base pair
@nl
prefLabel
Distinct domains of tRNA synthetase recognize the same base pair
@ast
Distinct domains of tRNA synthetase recognize the same base pair
@en
Distinct domains of tRNA synthetase recognize the same base pair
@nl
P2093
P3181
P356
P1433
P1476
Distinct domains of tRNA synthetase recognize the same base pair
@en
P2093
Eve Merriman
Kirk Beebe
Marissa Mock
Paul Schimmel
P2888
P3181
P356
10.1038/NATURE06454
P407
P577
2008-01-03T00:00:00Z
P6179
1003007797