Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis
about
Function, regulation and pathological roles of the Gab/DOS docking proteinsThe docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathwayMolecular basis of cleft palates in miceHGF/SF-met signaling in the control of branching morphogenesis and invasionInteraction domains: from simple binding events to complex cellular behaviorTyrosine phosphorylation of Grb2 by Bcr/Abl and epidermal growth factor receptor: a novel regulatory mechanism for tyrosine kinase signaling.Transcriptional repressor erf determines extraembryonic ectoderm differentiationEssential role for ERK2 mitogen-activated protein kinase in placental developmentPlacental alpha(2)-adrenoceptors control vascular development at the interface between mother and embryoMammalian Llgl2 is necessary for proper branching morphogenesis during placental developmentCell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental developmentCharacterization of mouse Rsk4 as an inhibitor of fibroblast growth factor-RAS-extracellular signal-regulated kinase signalinggrb2 heterozygosity rescues embryonic lethality but not tumorigenesis in pten+/- mice.Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.Altered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryosTargeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death.Development of structures and transport functions in the mouse placenta.Scaffolding protein Grb2-associated binder 1 sustains epidermal growth factor-induced mitogenic and survival signaling by multiple positive feedback loops.Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-betaAtypical RhoV and RhoU GTPases control development of the neural crest.Mathematical Justification of Expression-Based Pathway Activation Scoring (PAS).Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain.Essential role of growth factor receptor-mediated signal transduction through the mitogen-activated protein kinase pathway in early embryogenesis of the echinoderm.Grb2 signaling in cell motility and cancer
P2860
Q21245511-964DE498-9520-4BA3-A961-8D7D0CDF2949Q24799816-C68DBFDE-C0EE-4E89-9CBF-0434BC924B43Q26795762-1544A5E8-DC6D-408C-9471-75C861D46448Q28202466-A7850880-E3EA-4E04-B624-F4A8031219F0Q28209614-2CFB0F76-D5EE-48EE-A4B9-07C59129B1D7Q28365521-039E6B6D-95F1-425E-AC71-20B7CB02B585Q28505544-F2EB68FA-E7AC-4A5A-9E80-3A43C89E8CE1Q28510427-EAF9658A-09E9-4924-B390-57098A8B58D8Q28513384-7730FF38-F356-4106-BBD6-25201710F219Q28513494-F1554F10-BB3D-4786-9323-D037EECA82E0Q28513614-4B57BD4B-F270-4695-9C98-50A2F516D0EBQ28586563-3438D01C-92E7-4A9C-8B0B-7B479E6A5113Q30160821-37DBC1CC-5012-4EDE-B800-8367336EA108Q30480183-0D2738CF-A330-4D64-BCDA-77EA7C8DFC9AQ33297829-76E088F1-EADA-4168-8C3E-3FB89C5E0C7CQ35107897-10AB0EA1-3029-4005-9BD7-F93A03930FCBQ36124326-5443C3A4-A29B-4ADD-B368-8AD094B45778Q36559220-FAF3AD52-8EE5-4147-8CB7-9E8EF9E1CFBEQ37041510-CC9C5DFA-4A0C-4857-9AA6-40A35A9E45FFQ38006474-BD935C49-C135-4056-9643-3F44D9D8F38BQ38604285-8410F86E-AB6D-400C-9384-4B511D2954EBQ40645288-7169477A-2DC3-4548-B4B0-188A499F1DB6Q44188724-3B603415-F9FB-437A-A357-3A9B2A803877Q58199697-B27B8F6F-7BD7-41C9-AC7D-275519B595B0
P2860
Gene dosage-dependent functions for phosphotyrosine-Grb2 signaling during mammalian tissue morphogenesis
description
2001 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im Mai 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/05/01)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/05/01)
@nl
наукова стаття, опублікована в травні 2001
@uk
مقالة علمية (نشرت في مايو 2001)
@ar
name
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@ast
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@en
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@nl
type
label
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@ast
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@en
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@nl
prefLabel
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@ast
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@en
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@nl
P2093
P1433
P1476
Gene dosage-dependent function ...... mammalian tissue morphogenesis
@en
P2093
P304
P356
10.1016/S0960-9822(01)00198-1
P407
P577
2001-05-01T00:00:00Z