Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells
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Cks confers specificity to phosphorylation-dependent CDK signaling pathwaysThe APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exitCKS proteins protect mitochondrial genome integrity by interacting with mitochondrial single-stranded DNA-binding protein.Expression and biological-clinical significance of hTR, hTERT and CKS2 in washing fluids of patients with bladder cancer.Changes in granulosa cells gene expression associated with growth, plateau and atretic phases in medium bovine folliclesA novel synthetic 1,3-phenyl bis-thiourea compound targets microtubule polymerization to cause cancer cell death.FoxM1 is up-regulated by obesity and stimulates beta-cell proliferation.Over-expression of CKS1B activates both MEK/ERK and JAK/STAT3 signaling pathways and promotes myeloma cell drug-resistanceA central role for TRPS1 in the control of cell cycle and cancer development.Cks overexpression enhances chemotherapeutic efficacy by overriding DNA damage checkpoints.miR-26a and its target CKS2 modulate cell growth and tumorigenesis of papillary thyroid carcinomaIdentification and pharmacological inactivation of the MYCN gene network as a therapeutic strategy for neuroblastic tumor cellsExpression of cyclin kinase subunit 2 in human breast cancer and its prognostic significance.Comparison of gene expression patterns across 12 tumor types identifies a cancer supercluster characterized by TP53 mutations and cell cycle defectsTampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions.CKS2 in human cancers: Clinical roles and current perspectives (Review).Cyclin-dependent kinase subunit (Cks) 1 or Cks2 overexpression overrides the DNA damage response barrier triggered by activated oncoproteinsCks1 promotion of S phase entry and proliferation is independent of p27Kip1 suppressionUp-regulated CKS2 promotes tumor progression and predicts a poor prognosis in human colorectal cancerRho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesisCyclin-dependent kinase regulatory subunit 1 promotes cell proliferation by insulin regulation.The Prozone Effect Accounts for the Paradoxical Function of the Cdk-Binding Protein Suc1/CksCks1 enhances transcription efficiency at the GAL1 locus by linking the Paf1 complex to the 19S proteasomeTelmisartan exerts pleiotropic effects in endothelial cells and promotes endothelial cell quiescence and survival.Loss of cks1 homeostasis deregulates cell division cycle.The CDK subunit CKS2 counteracts CKS1 to control cyclin A/CDK2 activity in maintaining replicative fidelity and neurodevelopment.Increased expression of Cks1 protein is associated with lymph node metastasis and poor prognosis in nasopharyngeal carcinoma.Cks1: Structure, Emerging Roles and Implications in Multiple CancersFlipping the switch from g1 to s phase with e3 ubiquitin ligasesCryopreserved bovine spermatozoal transcript profile as revealed by high-throughput ribonucleic acid sequencing.Preliminary evidence for leukocyte transcriptional signatures for pediatric ventilator-associated pneumonia.Oncogenic potential of cyclin kinase subunit-2 in cholangiocarcinoma.Cancer specificity of promoters of the genes involved in cell proliferation controlUpregulation of miR-21 by Ras in vivo and its role in tumor growth.Expression and clinical significance of cyclin kinase subunit 2 in colorectal cancerOverexpression of CDC28 protein kinase regulatory subunit 1B confers an independent prognostic factor in nasopharyngeal carcinoma.Characteristics and clinical significance of cytogenetic abnormalities in polycythemia vera.CKS Proteins Promote Checkpoint Recovery by Stimulating Phosphorylation of Treslin.The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability.MicroRNA-26a inhibits proliferation and tumorigenesis via targeting CKS2 in laryngeal squamous cell carcinoma.
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P2860
Cyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cells
description
2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im September 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/09/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/09/01)
@nl
наукова стаття, опублікована у вересні 2008
@uk
مقالة علمية (نشرت في سبتمبر 2008)
@ar
name
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@ast
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@en
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@nl
type
label
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@ast
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@en
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@nl
prefLabel
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@ast
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@en
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@nl
P2093
P2860
P921
P356
P1476
Cyclin-dependent kinase-associ ...... e progression in somatic cells
@en
P2093
Björn Grünenfelder
Charles H. Spruck
Hanna-Stina Martinsson-Ahlzén
Steven I. Reed
Susana R. Chaves
Vasco Liberal
P2860
P304
P356
10.1128/MCB.01833-07
P407
P577
2008-09-01T00:00:00Z