Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
about
Targets of the Tal1 transcription factor in erythrocytes: E2 ubiquitin conjugase regulation by Tal1Structural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional TargetsHematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell CistromeThe TAL1/SCL transcription factor regulates cell cycle progression and proliferation in differentiating murine bone marrow monocyte precursorsSCL and associated proteins distinguish active from repressive GATA transcription factor complexesAngiopoietin-2 is a direct transcriptional target of TAL1, LYL1 and LMO2 in endothelial cellsDynamic transcription factor activity profiles reveal key regulatory interactions during megakaryocytic and erythroid differentiationDynamic shifts in occupancy by TAL1 are guided by GATA factors and drive large-scale reprogramming of gene expression during hematopoiesis.A 3-bp deletion in the HBS1L-MYB intergenic region on chromosome 6q23 is associated with HbF expressionRole of helix-loop-helix proteins during differentiation of erythroid cells.Transcription factor networks in erythroid cell and megakaryocyte developmentDynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration.GATA-binding protein 4 (GATA-4) and T-cell acute leukemia 1 (TAL1) regulate myogenic differentiation and erythropoietin response via cross-talk with Sirtuin1 (Sirt1)T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis.The NF-κB p65/miR-23a-27a-24 cluster is a target for leukemia treatmentSingle site-specific integration targeting coupled with embryonic stem cell differentiation provides a high-throughput alternative to in vivo enhancer analyses.Regions outside the DNA-binding domain are critical for proper in vivo specificity of an archetypal zinc finger transcription factorDynamic analysis of gene expression and genome-wide transcription factor binding during lineage specification of multipotent progenitors.Networking erythropoiesis.Concise review: Blood relatives: formation and regulation of hematopoietic stem cells by the basic helix-loop-helix transcription factors stem cell leukemia and lymphoblastic leukemia-derived sequence 1.Hematopoietic transcriptional mechanisms: from locus-specific to genome-wide vantage points.Impaired in vitro erythropoiesis following deletion of the Scl (Tal1) +40 enhancer is largely compensated for in vivo despite a significant reduction in expressionGenome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells.
P2860
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P2860
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
description
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
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im August 2008 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2008/08/15)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/08/15)
@nl
наукова стаття, опублікована в серпні 2008
@uk
مقالة علمية (نشرت في 15-8-2008)
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name
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
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Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@en
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@nl
type
label
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@ast
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@en
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@nl
prefLabel
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@ast
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@en
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@nl
P2093
P921
P1433
P1476
Differential use of SCL/TAL-1 DNA-binding domain in developmental hematopoiesis
@en
P2093
Catherine Porcher
Hedia Chagraoui
Mira T. Kassouf
P304
P356
10.1182/BLOOD-2007-12-128900
P407
P50
P577
2008-08-15T00:00:00Z