Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses
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Chikungunya virus induces IPS-1-dependent innate immune activation and protein kinase R-independent translational shutoffGenome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2pRegulation of antiviral innate immune signaling by stress-induced RNA granulesStress granules in the viral replication cycleAlpha/Beta Interferon Inhibits Cap-Dependent Translation of Viral but Not Cellular mRNA by a PKR-Independent MechanismStructural and Nonstructural Protein Genome Regions of Eastern Equine Encephalitis Virus Are Determinants of Interferon Sensitivity and Murine VirulenceCrystal Structures of GCN2 Protein Kinase C-terminal Domains Suggest Regulatory Differences in Yeast and MammalsEvidence that Yih1 resides in a complex with ribosomes.Phosphorylation of initiation factor eIF2 in response to stress conditions is mediated by acidic ribosomal P1/P2 proteins in Saccharomyces cerevisiae.Vaccine activation of the nutrient sensor GCN2 in dendritic cells enhances antigen presentationSystems biology approach predicts immunogenicity of the yellow fever vaccine in humansMumps Virus Induces Protein-Kinase-R-Dependent Stress Granules, Partly Suppressing Type III Interferon Production.Different effect of proteasome inhibition on vesicular stomatitis virus and poliovirus replication.Regulation of host translational machinery by African swine fever virus.Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production.Equine torovirus (BEV) induces caspase-mediated apoptosis in infected cellsInhibition of host translation by virus infection in vivo.Induction of GADD34 is necessary for dsRNA-dependent interferon-β production and participates in the control of Chikungunya virus infection.Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity.GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infectionRegulation of innate immunity by signaling pathways emerging from the endoplasmic reticulum.Negative regulation of IRF7 activation by activating transcription factor 4 suggests a cross-regulation between the IFN responses and the cellular integrated stress responses.Dengue virus modulates the unfolded protein response in a time-dependent mannerGCN2 in the brain programs PPARγ2 and triglyceride storage in the liver during perinatal development in response to maternal dietary fat.Virus infection rapidly activates the P58(IPK) pathway, delaying peak kinase activation to enhance viral replication.Increased susceptibility to DNA virus infection in mice with a GCN2 mutationProtein phosphatase 1 subunit Ppp1r15a/GADD34 regulates cytokine production in polyinosinic:polycytidylic acid-stimulated dendritic cells.The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanismLrABCF1, a GCN-type ATP-binding cassette transporter from Lilium regale, is involved in defense responses against viral and fungal pathogens.Translational control in synaptic plasticity and cognitive dysfunctionSevere acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activityLoss of the eukaryotic initiation factor 2α kinase general control nonderepressible 2 protects mice from pressure overload-induced congestive heart failure without affecting ventricular hypertrophy.25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.EIF2AK4 mutation in pulmonary veno-occlusive disease: A case report and review of the literaturePorcine Reproductive and Respiratory Syndrome Virus Infection Induces Stress Granule Formation Depending on Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK) in MARC-145 Cells.Regulation of stress granules in virus systemsTinkering with translation: protein synthesis in virus-infected cells.Mapping the crossroads of immune activation and cellular stress response pathways.A new paradigm: innate immune sensing of viruses via the unfolded protein response.Novel viral translation strategies.
P2860
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P2860
Antiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA viruses
description
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
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im April 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2006/04/19)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/04/19)
@nl
наукова стаття, опублікована у квітні 2006
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مقالة علمية (نشرت في 19-4-2006)
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name
Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
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Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
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Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
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type
label
Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
@ast
Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
@en
Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
@nl
prefLabel
Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
@ast
Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
@en
Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Antiviral effect of the mammal ...... inase GCN2 against RNA viruses
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P2093
César de Haro
Heather P. Harding
Iván Ventoso
Juan J. Berlanga
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601073
P407
P577
2006-04-19T00:00:00Z