Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development
about
Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairmentEosinophilia Associated with Disorders of Immune Deficiency or Immune DysregulationGenetic and structural validation of Aspergillus fumigatus N -acetylphosphoglucosamine mutase as an antifungal targetPGM3 mutations cause a congenital disorder of glycosylation with severe immunodeficiency and skeletal dysplasia.Disruption of O-GlcNAc Cycling in C. elegans Perturbs Nucleotide Sugar Pools and Complex Glycans.Glycans Instructing Immunity: The Emerging Role of Altered Glycosylation in Clinical Immunology.The roles of O-linked β-N-acetylglucosamine in cardiovascular physiology and disease.Transcriptomics of liver and muscle in Holstein cows genetically divergent for fertility highlight differences in nutrient partitioning and inflammation processes.Susceptibility to infections, without concomitant hyper-IgE, reported in 1976, is caused by hypomorphic mutation in the phosphoglucomutase 3 (PGM3) geneHypomorphic homozygous mutations in phosphoglucomutase 3 (PGM3) impair immunity and increase serum IgE levelsProtein O-GlcNAcylation is required for fibroblast growth factor signaling in Drosophila.Dynamic O-GlcNAcylation and its roles in the cellular stress response and homeostasis.O-GlcNAc and the cardiovascular system.Protein O-linked β-N-acetylglucosamine: a novel effector of cardiomyocyte metabolism and function.Primary Immunodeficiencies with Elevated IgE.Genetic Modifier Screens in Mice.Fatty acid synthase inhibits the O-GlcNAcase during oxidative stress.Roles of O-GlcNAcylation on amyloid-β precursor protein processing, tau phosphorylation, and hippocampal synapses dysfunction in Alzheimer's disease.Biology, Mechanism, and Structure of Enzymes in the α-d-Phosphohexomutase Superfamily.Detection of phosphoglucomutase-3 deficiency by lectin-based flow cytometry.Using Gene Essentiality and Synthetic Lethality Information to Correct Yeast and CHO Cell Genome-Scale Models.A simple and rapid method for measuring α-D-phosphohexomutases activity by using anion-exchange chromatography coupled with an electrochemical detector.Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation.A Novel PGM3 Mutation Is Associated With a Severe Phenotype of Bone Marrow Failure, Severe Combined Immunodeficiency, Skeletal Dysplasia, and Congenital Malformations.Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters.Inhibition of the Hexosamine Biosynthetic Pathway by targeting PGM3 causes breast cancer growth arrest and apoptosis.CDG Therapies: From Bench to Bedside.Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report
P2860
Q24338530-BE6994AA-5087-4D61-A8CB-18E53FF15B5FQ26799603-0790DA09-632D-47CA-A8E6-E74953D649ABQ27679053-5892ABE5-2769-4810-ABCC-1776D876E82DQ33858620-10EE6C5A-8AAC-485B-8C87-F5644A0378B1Q34562985-90EDD6CD-51DB-4C8F-B0D9-8C0E2A14375DQ35725275-FC25C694-D0D7-4A52-A377-B3131A012CB3Q35994096-16423BAF-57B9-4CEA-9A01-56AEA9BD9860Q36101702-517EEA41-8135-4A8B-8478-0647541868FFQ36416171-1E8D7A3F-DBA4-4DF6-BA26-F16319F72BE9Q36780978-ABE480B2-D31E-42E9-90BD-894027216A88Q36865176-AF066E1B-8268-4BA3-948C-363C39F42A96Q37099485-123F7ACC-15A9-4B92-99DA-583B3CE10B7AQ37619691-3AA52F65-0D89-4908-BA47-954C7E741094Q37924015-E13D8870-640C-4C1E-95B2-99E7A76096EDQ38477275-0061EA98-3C54-4B76-B410-4B766CF32560Q38526066-EB8A2BCC-EA83-428F-B000-964A811D5C09Q38715120-8BAFB510-A3CC-4147-A336-1A2D0D346C2DQ38808280-F79F1C75-16F4-4DEF-86E6-F07DD7506AA8Q40145092-0726DA5C-E050-4A62-8349-2A7F9016AD47Q40381251-9E9A3F67-F63E-4C1A-A0D1-ADA970B4E4FBQ40478667-1A6856DB-5B28-4536-BE33-F605DC361BF3Q41911431-9F420F49-091D-4451-88B5-447E34F941B2Q42743960-4C995A01-03AD-47AF-BB39-44FA3BA65B1BQ47881020-5381A27A-B397-45A4-A262-3399BB50229EQ50537421-59FF7A7E-0181-4836-AF0B-0CC337FFC8F2Q51743298-3CDD6C35-99D7-4A05-AF92-CEBEDBD8103CQ52558429-770CD785-655D-4D21-80AE-1A84C5F692FEQ58696278-92CF0B8F-FC28-49FB-A22F-E62FD04B583F
P2860
Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development
description
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im August 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/08/01)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/08/01)
@nl
наукова стаття, опублікована в серпні 2007
@uk
مقالة علمية (نشرت في أغسطس 2007)
@ar
name
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@ast
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@en
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@nl
type
label
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@ast
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@en
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@nl
prefLabel
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@ast
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@en
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@nl
P2093
P2860
P356
P1476
Agm1/Pgm3-mediated sugar nucle ...... hematopoiesis and development
@en
P2093
Carolyn de Graaf
Christian Kranz
Danielle L. Krebs
Douglas F. Hacking
Douglas J. Hilton
Hudson H. Freeze
Jennifer Antonchuk
Jian-Guo Zhang
Kylie T. Greig
P2860
P304
P356
10.1128/MCB.00802-07
P407
P577
2007-08-01T00:00:00Z