Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland
about
Expression and function of the homeodomain-containing protein Hex in thyroid cells.PAX8-mediated activation of the wt1 tumor suppressor geneAlternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation propertiesCongenital human thyroglobulin defect due to low expression of the thyroid-specific transcription factor TTF-1WBP-2, a WW domain binding protein, interacts with the thyroid-specific transcription factor Pax8Structural defects of a Pax8 mutant that give rise to congenital hypothyroidismThe paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcriptionRecovery of NIS expression in thyroid cancer cells by overexpression of Pax8 geneKidney regeneration: common themes from the embryo to the adultDevelopment of the Mammalian KidneyEya1 is required for the morphogenesis of mammalian thymus, parathyroid and thyroidRole of hindbrain in inner ear morphogenesis: analysis of Noggin knockout miceThyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroidPax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promotersNephric lineage specification by Pax2 and Pax8Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidneyDevelopment and morphogenesis of the Wolffian/epididymal duct, more twists and turnsNephrons require Rho-kinase for proximal-distal polarity developmentEvolution of developmental roles of Pax2/5/8 paralogs after independent duplication in urochordate and vertebrate lineages.Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene.An essential role for Pax8 in the transcriptional regulation of cadherin-16 in thyroid cells.Quantitative trait loci for energy balance traits in an advanced intercross line derived from mice divergently selected for heat loss.Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways.PAX8 Distinguishes Diffuse Large B-Cell Lymphoma Mimicking Sarcoma.Congenital urogenital abnormalities in children with congenital hypothyroidism.Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8.Distinct factors regulate the murine RAG-2 promoter in B- and T-cell lines.Identification of a novel pax8 gene sequence variant in four members of the same family: from congenital hypothyroidism with thyroid hypoplasia to mild subclinical hypothyroidism.PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein.Genome-wide analysis of Pax8 binding provides new insights into thyroid functions.Pax8 modulates the expression of Wnt4 that is necessary for the maintenance of the epithelial phenotype of thyroid cellsRole of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland.Inhibition of Pax2 Transcription Activation with a Small Molecule that Targets the DNA Binding Domain.Thyroid-specific transcription factors and their roles in thyroid cancer.A role for PAX8 in the tumorigenic phenotype of ovarian cancer cells.Clinical review: The emerging cell biology of thyroid stem cells.Identification of novel Pax8 targets in FRTL-5 thyroid cells by gene silencing and expression microarray analysisThyroid-specific inactivation of KIF3A alters the TSH signaling pathway and leads to hypothyroidism.Neuropilin-2 Is a Newly Identified Target of PAX8 in Thyroid Cells.A binding site for Pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord
P2860
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P2860
Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland
description
1990 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1990
@ast
im Oktober 1990 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1990/10/01)
@sk
vědecký článek publikovaný v roce 1990
@cs
wetenschappelijk artikel (gepubliceerd op 1990/10/01)
@nl
наукова стаття, опублікована в жовтні 1990
@uk
مقالة علمية (نشرت في أكتوبر 1990)
@ar
name
Pax8, a murine paired box gene ...... etory system and thyroid gland
@ast
Pax8, a murine paired box gene ...... etory system and thyroid gland
@en
Pax8, a murine paired box gene ...... etory system and thyroid gland
@nl
type
label
Pax8, a murine paired box gene ...... etory system and thyroid gland
@ast
Pax8, a murine paired box gene ...... etory system and thyroid gland
@en
Pax8, a murine paired box gene ...... etory system and thyroid gland
@nl
prefLabel
Pax8, a murine paired box gene ...... etory system and thyroid gland
@ast
Pax8, a murine paired box gene ...... etory system and thyroid gland
@en
Pax8, a murine paired box gene ...... etory system and thyroid gland
@nl
P2093
P3181
P1433
P1476
Pax8, a murine paired box gene ...... etory system and thyroid gland
@en
P2093
C. Walther
D. Plachov
J. L. Guenet
K. Chowdhury
P304
P3181
P407
P577
1990-10-01T00:00:00Z