The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane
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Characterization of TRIF selectivity in the AGP class of lipid A mimetics: role of secondary lipid chains.Monophosphoryl lipid A inhibits the cytokine response of endothelial cells challenged with LPS.CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin toleranceS100-alarmin-induced innate immune programming protects newborn infants from sepsis.TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target.Old and new adjuvants.Critical residues involved in Toll-like receptor 4 activation by cationic lipid nanocarriers are not located at the lipopolysaccharide-binding interface.Development of αGlcN(1↔1)αMan-based lipid A mimetics as a novel class of potent Toll-like receptor 4 agonists.Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex.Newborn susceptibility to infection vs. disease depends on complex in vivo interactions of host and pathogen.The adjuvant system AS01 up-regulates neutrophil CD14 expression and neutrophil-associated antigen transport in the local lymphatic network.Monophosphoryl lipid A-induced pro-inflammatory cytokine expression does not require CD14 in primary human dendritic cells.Specific features of human monocytes activation by monophosphoryl lipid A.Diverse pro-inflammatory endotoxin recognition systems of mammalian innate immunity.
P2860
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P2860
The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane
description
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
@ast
im Juni 2014 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2014/06/01)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/06/01)
@nl
наукова стаття, опублікована в червні 2014
@uk
مقالة علمية (نشرت في يونيو 2014)
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name
The attenuated inflammation of ...... complex at the plasma membrane
@ast
The attenuated inflammation of ...... complex at the plasma membrane
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The attenuated inflammation of ...... complex at the plasma membrane
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type
label
The attenuated inflammation of ...... complex at the plasma membrane
@ast
The attenuated inflammation of ...... complex at the plasma membrane
@en
The attenuated inflammation of ...... complex at the plasma membrane
@nl
prefLabel
The attenuated inflammation of ...... complex at the plasma membrane
@ast
The attenuated inflammation of ...... complex at the plasma membrane
@en
The attenuated inflammation of ...... complex at the plasma membrane
@nl
P2093
P2860
P921
P356
P1476
The attenuated inflammation of ...... complex at the plasma membrane
@en
P2093
Kensuke Miyake
Koichi Fukase
Natsuko Tanimura
Sachiko Akashi-Takamura
Shin-Ichiroh Saitoh
Toshiyuki Shimizu
Umeharu Ohto
P2860
P304
P356
10.1093/INTIMM/DXT071
P577
2014-06-01T00:00:00Z