Early embryonic lethality due to targeted inactivation of DNA ligase III
about
DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formationCrucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repairDNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cellsHuman RECQL5 participates in the removal of endogenous DNA damageDNA ligase III: a spotty presence in eukaryotes, but an essential function where testedFunctional redundancy between DNA ligases I and III in DNA replication in vertebrate cellsDNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repairEukaryotic DNA ligases: structural and functional insightsPartial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cellsHuman DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound statesRational design of human DNA ligase inhibitors that target cellular DNA replication and repairTwo DNA-binding and nick recognition modules in human DNA ligase IIIThe maintenance of mitochondrial DNA integrity--critical analysis and updateAlternative Okazaki Fragment Ligation Pathway by DNA Ligase IIIPathways for repairing and tolerating the spectrum of oxidative DNA lesionsMitochondrial DNA damage and its consequences for mitochondrial gene expressionOverview of base excision repair biochemistryBase excision repair and cancerRepair of persistent strand breaks in the mitochondrial genomeDNA ligases I and III cooperate in alternative non-homologous end-joining in vertebratesAn allelic series uncovers novel roles of the BRCT domain-containing protein PTIP in mouse embryonic vascular developmentX-ray repair cross complementing protein 1 in base excision repair.Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance.DNA ligases as therapeutic targetsScreen for mitochondrial DNA copy number maintenance genes reveals essential role for ATP synthaseMetabolism, genomics, and DNA repair in the mouse aging liver.Apoptosis induced by persistent single-strand breaks in mitochondrial genome: critical role of EXOG (5'-EXO/endonuclease) in their repairXRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes.Disconnecting XRCC1 and DNA ligase IIIDNA ligase I is not essential for mammalian cell viability.Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate InflammationFolate and colorectal cancer in rodents: a model of DNA repair deficiency.DNA-damage repair; the good, the bad, and the ugly.Poly(ADP-ribose) polymerase 1 regulates nuclear reprogramming and promotes iPSC generation without c-Myc.JWA regulates XRCC1 and functions as a novel base excision repair protein in oxidative-stress-induced DNA single-strand breaks.Direct and indirect roles of RECQL4 in modulating base excision repair capacity.Nuclear and mitochondrial DNA repair in selected eukaryotic aging model systems.DNA Ligases I and III Support Nucleotide Excision Repair in DT40 Cells with Similar Efficiency.The base excision repair pathway is required for efficient lentivirus integration.Base excision DNA repair levels in mitochondrial lysates of Alzheimer's disease.
P2860
Q21144955-89CD7451-8F91-48CD-A870-962749B43730Q24296083-57F0955F-ABE4-498D-BA2B-9243691DFB73Q24297891-BE0D4C5D-9745-443C-AEB2-FFD9023469EBQ24298591-CFC78554-32D2-404B-8ED3-40A3C0C7837EQ24603339-0E7A9DEC-1659-45AB-B8FA-D4C7C439CEDBQ24607753-2042A581-9D94-4C5B-8565-5099CA18C0AEQ24612486-9FFFC05F-0737-4759-94EB-7F60407B7CDFQ24617266-511DA845-42A9-4C9A-8C2D-F931B1964F2AQ24619372-AEEB0B73-E667-4980-9D34-8B375238872AQ24631008-3DEC3A26-9C4A-4511-AF3D-DF0651895C62Q24645423-9010B4D4-DA27-46E8-8753-35F99F69F264Q24646413-46CF7749-A4DF-4E38-B78E-B03AAF9A2DACQ26821907-BADFF0CF-21DC-43F9-9ADE-4D9A1DFE53A8Q26853144-444222F9-3EF6-4281-9056-6D9FBF412592Q26992194-BF7370C9-22BA-40B2-B9C1-C5BB94780E04Q27001150-C13F0BB4-8595-448D-A780-7EF5144CF986Q27021659-D9F2B2E5-65B2-49DE-B846-2634D34816E9Q27025537-12FEDF5C-C50F-4B7E-948C-248B27E35BA2Q27026352-42CC3775-D672-4302-BF79-07440F7AE21DQ28489091-703570DB-719B-4853-A9CA-138539CBD2FFQ28587411-985A6F50-E47D-4715-9E95-FCEBF508F7F8Q30458938-DF67C5C3-30B5-401C-9AC6-75F1AAB82684Q34359723-D026EB26-EABA-4CFB-A9FF-B13F2A13B12CQ34384677-6CE898F3-84BF-4180-91C0-55B2CE343ACAQ34692029-C742212E-0220-4056-A44D-993ED9ABAA42Q34922762-150681A5-A33A-4AAD-AE21-E1A0C968238AQ35213388-EBA27EC7-69C5-487C-9D85-453F7614AA91Q35441496-A8E86394-5EEA-4C85-A745-038E6C0EDED3Q35878514-F419517E-0045-4A5B-9F04-3DCBE9A5A3B7Q36120983-D94B8575-4168-4953-9ACA-CDE4A8692FBCQ36139765-4B8843FA-F58E-48F3-A744-52462E9B502EQ36326761-C55CF57A-5E40-4A8F-8665-C3C6A32ECC8EQ36487307-304DE812-15B7-4A5F-8502-5F6DD3ACE9E2Q36547699-D3954EA7-4B00-4226-8F21-63061840500CQ37149786-214CBE41-E5AD-4715-A11C-AFE3ADE88972Q37312504-E4BFBB79-28C4-4E36-87D7-AC7374A0DCE2Q38050774-EC8C5266-B179-4872-9752-FF16C73E83C9Q38858211-E4CFDD7B-0A74-4FE1-8E06-7AB27205D52FQ39568581-2AC7AA0D-41EE-4ED4-98D7-B88761D7CB62Q41562755-F8CC03D6-4587-4170-B2E6-4E7A424E41C8
P2860
Early embryonic lethality due to targeted inactivation of DNA ligase III
description
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Mai 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/05/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/05/01)
@nl
наукова стаття, опублікована в травні 2006
@uk
مقالة علمية (نشرت في مايو 2006)
@ar
name
Early embryonic lethality due to targeted inactivation of DNA ligase III
@ast
Early embryonic lethality due to targeted inactivation of DNA ligase III
@en
Early embryonic lethality due to targeted inactivation of DNA ligase III
@nl
type
label
Early embryonic lethality due to targeted inactivation of DNA ligase III
@ast
Early embryonic lethality due to targeted inactivation of DNA ligase III
@en
Early embryonic lethality due to targeted inactivation of DNA ligase III
@nl
prefLabel
Early embryonic lethality due to targeted inactivation of DNA ligase III
@ast
Early embryonic lethality due to targeted inactivation of DNA ligase III
@en
Early embryonic lethality due to targeted inactivation of DNA ligase III
@nl
P2093
P2860
P1476
Early embryonic lethality due to targeted inactivation of DNA ligase III
@en
P2093
Chengming Zhu
Devin B. Lacey
Frederick W. Alt
Nahum Puebla-Osorio
P2860
P304
P356
10.1128/MCB.26.10.3935-3941.2006
P407
P577
2006-05-01T00:00:00Z