p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
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Stathmin is dispensable for tumor onset in miceFez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development.MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitorsRSK1 drives p27Kip1 phosphorylation at T198 to promote RhoA inhibition and increase cell motility.Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs)Extra-cell cycle regulatory functions of cyclin-dependent kinases (CDK) and CDK inhibitor proteins contribute to brain development and neurological disordersCaspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasionRole of T198 modification in the regulation of p27(Kip1) protein stability and functionMislocalization of p27 to the cytoplasm of breast cancer cells confers resistance to anti-HER2 targeted therapyThe N-terminal region of p27 inhibits HIF-1α protein translation in ribosomal protein S6-dependent manner by regulating PHLPP-Ras-ERK-p90RSK axisSCLIP, a microtubule-destabilizing factor, interacts with RasGRF1 and inhibits its ability to promote Rac activation and neurite outgrowthPhosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rateThe tumor suppressor functions of p27(kip1) include control of the mesenchymal/amoeboid transition.p27kip1 controls cell morphology and motility by regulating microtubule-dependent lipid raft recycling.Determination of metastasis-associated proteins in non-small cell lung cancer by comparative proteomic analysis.Gene expression profiles in mouse embryo fibroblasts lacking stathmin, a microtubule regulatory protein, reveal changes in the expression of genes contributing to cell motility.p27Kip1 promotes invadopodia turnover and invasion through the regulation of the PAK1/Cortactin pathway.Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent mannerEffect of leptin on mouse trophoblast giant cells.Endothelial deletion of Sag/Rbx2/Roc2 E3 ubiquitin ligase causes embryonic lethality and blocks tumor angiogenesis.Loss of p27kip1 increases genomic instability and induces radio-resistance in luminal breast cancer cells.Inhibition of PI-3K restores nuclear p27Kip1 expression in a mouse model of Kras-driven lung cancer.p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells.Drosophila stathmins bind tubulin heterodimers with high and variable stoichiometries.Loss of p27 upregulates MnSOD in a STAT3-dependent manner, disrupts intracellular redox activity and enhances cell migration.A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis.Brachyury regulates proliferation of cancer cells via a p27Kip1-dependent pathwayPolyploid giant cancer cells with budding and the expression of cyclin E, S-phase kinase-associated protein 2, stathmin associated with the grading and metastasis in serous ovarian tumor.Systematic analysis of the transcriptional switch inducing migration of border cells.A new tumour suppression mechanism by p27Kip1: EGFR down-regulation mediated by JNK/c-Jun pathway inhibition.Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.Movers and shakers: cell cytoskeleton in cancer metastasis.The RB-E2F1 pathway regulates autophagy.Stathmin1 regulates p27 expression, proliferation and drug resistance, resulting in poor clinical prognosis in cholangiocarcinoma.RETRACTED: STMN-1 is a potential marker of lymph node metastasis in distal esophageal adenocarcinomas and silencing its expression can reverse malignant phenotype of tumor cells.Siva1 suppresses epithelial-mesenchymal transition and metastasis of tumor cells by inhibiting stathmin and stabilizing microtubulesStathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas.The prognostic value and therapeutic target role of stathmin-1 in urinary bladder cancermiR-221 facilitates the TGFbeta1-induced epithelial-mesenchymal transition in human bladder cancer cells by targeting STMN1.SEPTIN2 and STATHMIN Regulate CD99-Mediated Cellular Differentiation in Hodgkin's Lymphoma.
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P2860
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
description
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artikull shkencor
@sq
artículu científicu espublizáu en 2005
@ast
im Januar 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2005
@uk
مقالة علمية (نشرت عام 2005)
@ar
name
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@ast
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@en
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@nl
type
label
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@ast
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@en
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@nl
prefLabel
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@ast
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@en
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@nl
P2093
P50
P3181
P1433
P1476
p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion
@en
P2093
Andrea Morrione
Milena S Nicoloso
Vincenzo Canzonieri
P3181
P356
10.1016/J.CCR.2004.11.025
P50
P577
2005-01-01T00:00:00Z