Growth retardation and early death of beta-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells
about
Cloning of a novel member of the UDP-galactose:beta-N-acetylglucosamine beta1,4-galactosyltransferase family, beta4Gal-T4, involved in glycosphingolipid biosynthesisThree proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathwayA family of human beta4-galactosyltransferases. Cloning and expression of two novel UDP-galactose:beta-n-acetylglucosamine beta1, 4-galactosyltransferases, beta4Gal-T2 and beta4Gal-T3Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal:GlcNAc beta-1,4-galactosyltransferaseExpression of Tas1 taste receptors in mammalian spermatozoa: functional role of Tas1r1 in regulating basal Ca²⁺ and cAMP concentrations in spermatozoaGeneration of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulationGalactosylation of N-linked oligosaccharides by human beta-1,4-galactosyltransferases I, II, III, IV, V, and VI expressed in Sf-9 cellsKnockout of mouse beta 1,4-galactosyltransferase-1 gene results in a dramatic shift of outer chain moieties of N-glycans from type 2 to type 1 chains in hepatic membrane and plasma glycoproteinsEx vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heartMice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome traffickingLearning/memory impairment and reduced expression of the HNK-1 carbohydrate in beta4-galactosyltransferase-II-deficient miceImpairment of skin wound healing in beta-1,4-galactosyltransferase-deficient mice with reduced leukocyte recruitmentBiosynthetic processing of cathepsins and lysosomal degradation are abolished in asparaginyl endopeptidase-deficient miceReduced susceptibility to colitis-associated colon carcinogenesis in mice lacking plasma membrane-associated sialidaseChinese hamster ovary (CHO) cells may express six beta 4-galactosyltransferases (beta 4GalTs). Consequences of the loss of functional beta 4GalT-1, beta 4GalT-6, or both in CHO glycosylation mutants.The chicken genome contains two functional nonallelic beta1,4-galactosyltransferase genes. Chromosomal assignment to syntenic regions tracks fate of the two gene lineages in the human genome.Promoter DNA methylation of oncostatin m receptor-beta as a novel diagnostic and therapeutic marker in colon cancer.Protein glycosylation in development and disease.Evolutionary considerations in relating oligosaccharide diversity to biological function.Mural granulosa cell gene expression associated with oocyte developmental competenceFertilization: a sperm's journey to and interaction with the oocyte.Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1Glycoprotein hyposialylation gives rise to a nephrotic-like syndrome that is prevented by sialic acid administration in GNE V572L point-mutant mice.Glycosylation regulates Notch signalling.Male infertility and the genetics of spermatogenesisGalactose-extended glycans of antibodies produced by transgenic plants.Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId.Disruption of Smad4 expression in T cells leads to IgA nephropathy-like manifestations.Mice overexpressing β-1,4-Galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitisFunctional roles for beta1,4-N-acetlygalactosaminyltransferase-A in Drosophila larval neurons and muscles.Gamete recognition in mice depends on the cleavage status of an egg's zona pellucida protein.Role of a single amino acid in the evolution of glycans of invertebrates and vertebratesDevelopment of immunoglobulin A nephropathy- like disease in beta-1,4-galactosyltransferase-I-deficient miceMechanisms of fertilization elucidated by gene-manipulated animalsHuman sperm bind to the N-terminal domain of ZP2 in humanized zonae pellucidae in transgenic mice.Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient miceRNA-Sequencing for profiling goat milk transcriptome in colostrum and mature milk.Large-scale identification of target proteins of a glycosyltransferase isozyme by Lectin-IGOT-LC/MS, an LC/MS-based glycoproteomic approachProduction of mice deficient in genes for interleukin (IL)-1alpha, IL-1beta, IL-1alpha/beta, and IL-1 receptor antagonist shows that IL-1beta is crucial in turpentine-induced fever development and glucocorticoid secretion.The molecular basis of gamete recognition in mice and humans
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P2860
Growth retardation and early death of beta-1,4-galactosyltransferase knockout mice with augmented proliferation and abnormal differentiation of epithelial cells
description
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
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artículu científicu espublizáu en 1997
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im April 1997 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 1997/04/15)
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vědecký článek publikovaný v roce 1997
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wetenschappelijk artikel (gepubliceerd op 1997/04/15)
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наукова стаття, опублікована у квітні 1997
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مقالة علمية (نشرت في 15-4-1997)
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name
Growth retardation and early d ...... rentiation of epithelial cells
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Growth retardation and early d ...... rentiation of epithelial cells
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Growth retardation and early d ...... rentiation of epithelial cells
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type
label
Growth retardation and early d ...... rentiation of epithelial cells
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Growth retardation and early d ...... rentiation of epithelial cells
@en
Growth retardation and early d ...... rentiation of epithelial cells
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prefLabel
Growth retardation and early d ...... rentiation of epithelial cells
@ast
Growth retardation and early d ...... rentiation of epithelial cells
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Growth retardation and early d ...... rentiation of epithelial cells
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P2093
P2860
P356
P1433
P1476
Growth retardation and early d ...... rentiation of epithelial cells
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P2093
P2860
P304
P356
10.1093/EMBOJ/16.8.1850
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P577
1997-04-01T00:00:00Z