Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2
about
Dab2 is a key regulator of endocytosis and post-endocytic trafficking of the cystic fibrosis transmembrane conductance regulatorThe adaptor protein Disabled-2: new insights into platelet biology and integrin signalingEndocytosis and Physiology: Insights from Disabled-2 Deficient MiceCIN85 modulates TGFβ signaling by promoting the presentation of TGFβ receptors on the cell surface.Disabled homolog 2 controls macrophage phenotypic polarization and adipose tissue inflammationEngulfment protein GULP is regulator of transforming growth factor-β response in ovarian cells.Dab2 attenuates brain injury in APP/PS1 mice via targeting transforming growth factor-beta/SMAD signaling.Differential regulation of Smad3 and of the type II transforming growth factor-β receptor in mitosis: implications for signalingDifferential requirement for Dab2 in the development of embryonic and extra-embryonic tissues.Loss of Dab2 expression in breast cancer cells impairs their ability to deplete TGF-β and induce Tregs development via TGF-β.Regulation of TGF-β receptor activityRole of FQQI motif in the internalization, trafficking, and signaling of guanylyl-cyclase/natriuretic peptide receptor-A in cultured murine mesangial cellsRetromer maintains basolateral distribution of the type II TGF-β receptor via the recycling endosome.Noncanonical TGF-β signaling during mammary tumorigenesis.The relevance of the TGF-β Paradox to EMT-MET programsTargeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-βSAMP8 mice have altered hippocampal gene expression in long term potentiation, phosphatidylinositol signaling, and endocytosis pathways.Disabled-2 is a negative immune regulator of lipopolysaccharide-stimulated Toll-like receptor 4 internalization and signaling.BMP signaling requires retromer-dependent recycling of the type I receptor.A novel multi-network approach reveals tissue-specific cellular modulators of fibrosis in systemic sclerosis.Post-translational regulation of TGF-β receptor and Smad signaling.Disabled-2: A modular scaffold protein with multifaceted functions in signaling.TGF-β Signaling from Receptors to Smads.Signaling Receptors for TGF-β Family Members.Dab2 inhibits the cholesterol-dependent activation of JNK by TGF-βNeuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta.Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2.Micro ribonucleic acid-93 promotes proliferation and migration of esophageal squamous cell carcinoma by targeting disabled 2Basolateral delivery of the type I transforming growth factor beta receptor is mediated by a dominant-acting cytoplasmic motif.Intracellular trafficking of transforming growth factor β receptors.Deficiency of Dab2 (Disabled Homolog 2) in Myeloid Cells Exacerbates Inflammation in Liver and Atherosclerotic Plaques in LDLR (Low-Density Lipoprotein Receptor)-Null Mice-Brief Report
P2860
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P2860
Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2
description
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im November 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/11/15)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/11/15)
@nl
наукова стаття, опублікована в листопаді 2010
@uk
مقالة علمية (نشرت في 15-11-2010)
@ar
name
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@ast
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@en
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@nl
type
label
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@ast
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@en
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@nl
prefLabel
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@ast
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@en
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@nl
P2093
P2860
P3181
P356
P1476
Type II transforming growth fa ...... clathrin adaptor protein Dab2
@en
P2093
Claire E. Repellin
Edward B. Leof
Mark C. Wilkes
Maryanne Edens
Philip H. Howe
Raman Deep Singh
Richard E. Pagano
Sumedha G. Penheiter
P2860
P304
P3181
P356
10.1091/MBC.E09-12-1019
P577
2010-11-15T00:00:00Z