LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
about
Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signalingLKB1 mediates the development of conventional and innate T cells via AMP-dependent kinase autonomous pathways.CBAP promotes thymocyte negative selection by facilitating T-cell receptor proximal signalingThe liver kinase B1 is a central regulator of T cell development, activation, and metabolism.LKB1 inhibition of NF-κB in B cells prevents T follicular helper cell differentiation and germinal center formation.Regulation and function of mTOR signalling in T cell fate decisions.An Lck-cre transgene accelerates autoantibody production and lupus development in (NZB × NZW)F1 mice.Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolismProtein kinase D regulates positive selection of CD4(+) thymocytes through phosphorylation of SHP-1.mTOR and metabolic pathways in T cell quiescence and functional activation.Germinal center kinases in immune regulation.LKB1 and AMPK: central regulators of lymphocyte metabolism and function.At the crossroad of T cells, adipose tissue, and diabetes.Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib.Arp2/3 complex controls T cell homeostasis by maintaining surface TCR levels via regulating TCR+ endosome traffickingThe mediator subunit Med23 contributes to controlling T-cell activation and prevents autoimmunity.MicroRNA-17 promotes normal ovarian cancer cells to cancer stem cells development via suppression of the LKB1-p53-p21/WAF1 pathway.The long-term survival potential of mature T lymphocytes is programmed during development in the thymus.SIRT3 Protects Rotenone-induced Injury in SH-SY5Y Cells by Promoting Autophagy through the LKB1-AMPK-mTOR Pathway.
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LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
description
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
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im Mai 2011 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2011/05/18)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/05/18)
@nl
наукова стаття, опублікована в травні 2011
@uk
مقالة علمية (نشرت في 18-5-2011)
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name
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@ast
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@en
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
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type
label
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@ast
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@en
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@nl
prefLabel
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@ast
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@en
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@nl
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LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
@en
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Haifeng Liu
Hongbin Ji
Xiaolong Liu
Yonghao Cao
Zichun Hua
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P304
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10.1038/EMBOJ.2011.116
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P577
2011-05-18T00:00:00Z