Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
about
Immune evasion and recognition of the syphilis spirochete in blood and skin of secondary syphilis patients: two immunologically distinct compartmentsSecondary syphilis: the classical triad of skin rash, mucosal ulceration and lymphadenopathyBorrelia garinii induces CXCL13 production in human monocytes through Toll-like receptor 2Borrelia burgdorferi changes its surface antigenic expression in response to host immune responsesDirect Toll-like receptor 2 mediated co-stimulation of T cells in the mouse system as a basis for chronic inflammatory joint diseaseImmunology of term and preterm laborToll-like receptor cascade and gene polymorphism in host-pathogen interaction in Lyme diseaseBeyond empiricism: informing vaccine development through innate immunity researchSystems biology applied to vaccine and immunotherapy developmentForward genetic approaches for elucidation of novel regulators of Lyme arthritis severityAntagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and ArthritisInteraction of differentiated human adipocytes with macrophages leads to trogocytosis and selective IL-6 secretion.Location, location, location: is membrane partitioning everything when it comes to innate immune activation?Mechanisms of Borrelia burgdorferi internalization and intracellular innate immune signalingCD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferiTLR8 deficiency leads to autoimmunity in miceTRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathwayMycobacterial lipoarabinomannan mediates physical interactions between TLR1 and TLR2 to induce signalingInnate immune function of the neisserial porins and the relationship to vaccine adjuvant activityTLR2 activation inhibits embryonic neural progenitor cell proliferationLysosomal β-glucuronidase regulates Lyme and rheumatoid arthritis severity.TLR1/TLR2 heterodimers play an important role in the recognition of Borrelia spirochetesImmunogenomics and systems biology of vaccines.Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation.FimH adhesin of type 1 fimbriae is a potent inducer of innate antimicrobial responses which requires TLR4 and type 1 interferon signalling.Activation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-beta.Relative contributions of innate and acquired host responses to bacterial control and arthritis development in Lyme diseaseIncreased TLR4 expression and downstream cytokine production in immunosuppressed adults compared to non-immunosuppressed adults.Activation of the TLR1/2 pathway induces the shaping of the immune response status of peripheral blood leukocytes.Toll-like receptors 1 and 2 heterodimers alter Borrelia burgdorferi gene expression in mice and ticks.Pattern recognition via the toll-like receptor system in the human female genital tract.Differential effect of TLR2 and TLR4 on the immune response after immunization with a vaccine against Neisseria meningitidis or Bordetella pertussis.MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi.Lipoprotein-dependent and -independent immune responses to spirochetal infection.FimH can directly activate human and murine natural killer cells via TLR4Toll-like receptor 2 mediates inhibition of HCO(3)(-) absorption by bacterial lipoprotein in medullary thick ascending limbCharacteristic changes in microbial community composition and expression of innate immune genes in acute appendicitis.Different patterns of expression and of IL-10 modulation of inflammatory mediators from macrophages of Lyme disease-resistant and -susceptible mice.TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells.Borrelia burgdorferi arthritis-associated locus Bbaa1 regulates Lyme arthritis and K/B×N serum transfer arthritis through intrinsic control of type I IFN production.
P2860
Q21144775-DCD14973-20AF-46A5-B7A9-2C383699886BQ22241585-A0B468F6-5300-4BA0-AF7D-882FC804E4E5Q24309415-4BE40BCA-0BAE-41D0-B507-9BE3C1043EA2Q24561576-5DA1EE82-41E0-43D4-9B36-045EEFA63102Q24796731-DA87BCFD-94D6-45BA-9474-F92DA433AF9BQ24801342-A592AE0B-4EF9-4EC0-B8E5-542E6A2FCD0FQ26744045-051CA3DC-2D56-455C-8F53-741485565452Q26824573-D0D757DB-AAC7-4673-93F3-9A4E4BB808E4Q26830374-E0A5CEE2-1DF0-45BC-8556-C08FA3BDBE5FQ26998992-5D122053-C23D-4355-8238-C84A9EFF8B6DQ27300844-E4E86D1E-296A-410A-8CE4-FBD51C36AAD6Q27330460-80F2A663-43B9-4108-8143-7FC6B9BC648FQ27693270-39E9B35D-DEB6-4135-A59C-F2923AA148F0Q28087160-32F62FDA-6934-4A89-94A5-3127858E948AQ28257106-788A3BC5-B0E0-4EF4-B4B8-34445EE0F1A5Q28292240-2FE829CF-BF16-4BD6-AF1B-48F0E7F4B21EQ28505835-FD51ADA2-EDEB-41A0-8FEB-0ADF36BFA5C1Q29030022-9922F2E1-2393-4BA4-B330-2FA6E69850B5Q30156878-76997B4B-E767-40E0-A5E3-24DAE549D41CQ30495687-CF327268-CEB0-430B-A8F5-2B76037C50B7Q30560471-E222CC70-A63A-49D4-8A4D-FB9630205787Q31037925-62043D50-8CA7-4C76-9CA9-9BECB9150967Q33350387-87444FDF-1CD9-4C7D-8235-2A496859B7A2Q33378891-AB17D078-CD73-4FF3-8C22-B056A2B841BDQ33389846-959E9A31-3A22-430C-AA97-E18F8E940158Q33450590-78D9EFAD-7333-4D73-ADEE-F1C284A3E7E4Q33558655-D690EB96-A788-4DAF-836F-3ABEE68F88AEQ33623765-3AAD57C3-E35A-4473-ABED-6FF69D701496Q33706201-AB6920C8-A632-4751-ABE7-55117A3E897BQ33756345-E150F9B4-8B4A-42F5-96E0-8513BE414772Q33783020-34153D24-08DF-4C36-866D-C15F9E642E85Q33784386-62A4946C-AB11-4EBC-939B-F4BDAF3AD4ADQ33812777-1E1DB6D5-7B18-48B0-9849-331AA327FBE0Q33910726-9C245070-85D5-49C5-9E9A-45CBF9560657Q34025104-127F7C89-729C-437B-8E45-20A01C94D943Q34149622-456D199A-7F70-41AB-BE3A-666C69DD2A3AQ34391698-23AAE62C-CC47-4F31-B2B3-58ACF864C233Q34424975-4100337F-353E-489D-AA84-BFDFEF1279F9Q34468344-86B66914-5A37-4CF7-81AE-3C944FC054E0Q34646554-7202CBA7-8BD2-4D32-9905-F28B62C2D397
P2860
Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im August 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/08/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/01)
@nl
наукова стаття, опублікована в серпні 2002
@uk
مقالة علمية (نشرت في أغسطس 2002)
@ar
name
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@ast
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@en
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@nl
type
label
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@ast
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@en
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@nl
prefLabel
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@ast
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@en
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Hyporesponsiveness to vaccinat ...... TLR1- and TLR2-deficient mice
@en
P2093
Lena Alexopoulou
Markus Schnare
Richard A. Flavell
Robert T. Schoen
Venetta Thomas
Yves Lobet
P2860
P2888
P304
P3181
P356
10.1038/NM732
P407
P577
2002-08-01T00:00:00Z