Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
about
Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triadB Lymphocyte-Specific Loss of Ric-8A Results in a Gα Protein Deficit and Severe Humoral Immunodeficiency.Ablation of RIC8A function in mouse neurons leads to a severe neuromuscular phenotype and postnatal deathRic-8: different cellular roles for a heterotrimeric G-protein GEF.Dictyostelium Ric8 is a nonreceptor guanine exchange factor for heterotrimeric G proteins and is important for development and chemotaxis.The guanine nucleotide exchange factor Ric-8A induces domain separation and Ras domain plasticity in Gαi1.GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation.Expression Pattern and Localization Dynamics of Guanine Nucleotide Exchange Factor RIC8 during Mouse Oogenesis.Ric-8A gene deletion or phorbol ester suppresses tumorigenesis in a mouse model of GNAQ(Q209L)-driven melanoma.Drosophila Ric-8 interacts with the Gα12/13 subunit, Concertina, during activation of the Folded gastrulation pathway.Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane associationRic-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα.Ric-8 regulation of heterotrimeric G proteins.Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.The impact of RGS and other G-protein regulatory proteins on Gαi-mediated signaling in immunity.The CREB Transcription Factor Controls Transcriptional Activity of the Human RIC8B Gene.The Ric-8B gene is highly expressed in proliferating preosteoblastic cells and downregulated during osteoblast differentiation in a SWI/SNF- and C/EBPbeta-mediated manner.Deletion of RIC8A in neural precursor cells leads to altered neurogenesis and neonatal lethality of mouse.
P2860
Q26999408-FE2127F9-6BA4-41DB-A591-1303E1A728F5Q27302329-B0F0682D-488B-4CB3-8FC9-22FA324EA67CQ27307146-57820881-541D-4CAF-B00E-DAC03F7A235CQ30415516-322D1518-C808-4282-B1EE-237BE5EFCD91Q30539049-B47E4EE4-F407-49C2-8D9A-30896812AE85Q35062664-44E1493C-FF68-4D3C-90CC-EEFF83CD6BFEQ35172574-A7622874-EBCE-4662-B6B8-A22594A2C232Q35660212-5AF7D70C-B03F-4D06-A4E5-32E88F4C15BEQ37096232-1E9AE573-6AED-45B1-8438-DE838B1DB6E3Q37283403-5FC17F6C-83E4-4932-B326-054D31515C46Q37408332-ECD5434B-9FF0-4845-BD57-86F3F07CFA92Q37530904-BD73A0CA-5B4C-4127-9D33-4A1D89B2FDA7Q38079286-E52B85CA-DD3D-41F7-A062-9E1500787AB9Q38734798-80775F51-2272-4AB1-806A-85E3DA5B3347Q38806373-3975463A-6F76-4573-81F7-687C248C00F1Q38806626-B680B0EF-BC82-4A78-AF65-7164902C2B09Q39537696-A27F63AD-327D-4C52-AC3D-A0CF0FF42913Q41495770-2559C844-807C-4BCE-B009-97120FB19CB0
P2860
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
description
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Dezember 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/12/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/12/01)
@nl
наукова стаття, опублікована в грудні 2010
@uk
مقالة علمية (نشرت في ديسمبر 2010)
@ar
name
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@ast
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@en
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@nl
type
label
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@ast
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@en
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@nl
prefLabel
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@ast
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@en
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@nl
P2093
P2860
P3181
P356
P1476
Nucleotide exchange factor RIC-8 is indispensable in mammalian early development
@en
P2093
Alar Karis
Katrin Ruisu
Merly Saare
Riho Meier
Sirje Lulla
Tambet Tõnissoo
P2860
P304
P3181
P356
10.1002/DVDY.22480
P50
P577
2010-12-01T00:00:00Z