GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation. - Wikidata - wikimedia - TriplyDB

GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation.

GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation.

http://www.wikidata.org/entity/Q35172574

about

Outside-in signaling--a brief review of GPCR signaling with a focus on the Drosophila GPCR family Accessory proteins for heterotrimeric G-proteins in the kidney Heterotrimeric G proteins as emerging targets for network based therapy in cancer: End of a long futile campaign striking heads of a Hydra A Conserved Role for Girdin in Basal Body Positioning and Ciliogenesis G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2 Activation of Gαi at the Golgi by GIV/Girdin imposes finiteness in Arf1 signaling.Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors.Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy Determinant role for the gep oncogenes, Gα12/13, in ovarian cancer cell proliferation and xenograft tumor growth.Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.Focal adhesions are foci for tyrosine-based signal transduction via GIV/Girdin and G proteins.Evolutionary Conservation of a GPCR-Independent Mechanism of Trimeric G Protein Activation Prognostic Impact of Modulators of G proteins in Circulating Tumor Cells from Patients with Metastatic Colorectal Cancer.GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Creates a Positive Feedback Loop That Potentiates Outside-in Integrin Signaling in Cancer Cells.Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells.Girdin (GIV) Expression as a Prognostic Marker of Recurrence in Mismatch Repair-Proficient Stage II Colon Cancer GIV/Girdin activates Gαi and inhibits Gαs via the same motif Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.Discs large homolog 5 decreases formation and function of invadopodia in human hepatocellular carcinoma via Girdin and Tks5.Regulation, Signaling, and Physiological Functions of G-Proteins.Physical and Chemical Gradients in the Tumor Microenvironment Regulate Tumor Cell Invasion, Migration, and Metastasis.The Gαi-GIV binding interface is a druggable protein-protein interaction PAQR3 regulates Golgi vesicle fission and transport via the Gβγ-PKD signaling pathway.Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-Binding and Activating motif.G protein coupled growth factor receptor tyrosine kinase: no longer an oxymoron.Prognostic impact of total and tyrosine phosphorylated GIV/Girdin in breast cancers.Thematic minireview series: cell biology of G protein signaling.Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein.When Heterotrimeric G Proteins Are Not Activated by G Protein-Coupled Receptors: Structural Insights and Evolutionary Conservation.Rapid kinetic BRET measurements to monitor G protein activation by GPCR and non-GPCR proteins.Fluorescence polarization assays to measure interactions between Gα subunits of heterotrimeric G proteins and regulatory motifs.Girdin protein: A potential metastasis predictor associated with prognosis in lung cancer.Cell Migration in Microfabricated 3D Collagen Microtracks is Mediated through the Prometastatic Protein Girdin.A biochemical and genetic discovery pipeline identifies PLCδ4b as a nonreceptor activator of heterotrimeric G-proteins

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P2860

GIV/Girdin transmits signals from multiple receptors by triggering trimeric G protein activation.

http://www.wikidata.org/entity/Q35172574

description

2015 nî lūn-bûn

@nan

2015 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

GIV/Girdin transmits signals f ...... trimeric G protein activation.

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GIV/Girdin transmits signals f ...... trimeric G protein activation.

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type

label

GIV/Girdin transmits signals f ...... trimeric G protein activation.

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GIV/Girdin transmits signals f ...... trimeric G protein activation.

@en

prefLabel

GIV/Girdin transmits signals f ...... trimeric G protein activation.

@ast

GIV/Girdin transmits signals f ...... trimeric G protein activation.

@en

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JBC.R114.613414

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Journal of Biological Chemistry

P1476

GIV/Girdin transmits signals f ...... trimeric G protein activation.

@en

P2093

Mikel Garcia-Marcos

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Pradipta Ghosh

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P2860

Activation of heterotrimeric G-protein signaling by a ras-related protein. Implications for signal integration

Identification and characterization of GIV, a novel Galpha i/s-interacting protein found on COPI, endoplasmic reticulum-Golgi transport vesicles

STAT3 protein up-regulates Gα-interacting vesicle-associated protein (GIV)/Girdin expression, and GIV enhances STAT3 activation in a positive feedback loop during wound healing and tumor invasion/metastasis

A novel hook-related protein family and the characterization of hook-related protein 1

GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domain

Akt/PKB regulates actin organization and cell motility via Girdin/APE

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family

GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits

Activator of G protein signaling 3 is a guanine dissociation inhibitor for Galpha i subunits

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

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6697-6704

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scholarly article

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10.1074/JBC.R114.613414

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11

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290

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Marilyn Farquhar

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2015-01-20T00:00:00Z

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4358093

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