Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
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Capture of microtubule plus-ends at the actin cortex promotes axophilic neuronal migration by enhancing microtubule tension in the leading processThe cytoskeletal protein Ndel1 regulates dynamin 2 GTPase activityCalcium release-dependent actin flow in the leading process mediates axophilic migrationGet to grips: steering local actin dynamics with IQGAPsIQGAPs in cancer: a family of scaffold proteins underlying tumorigenesisThe biology of IQGAP proteins: beyond the cytoskeletonNeuronal migration and its disorders affecting the CA3 regionCadherin-2 controls directional chain migration of cerebellar granule neuronsIQGAP1 stimulates proliferation and enhances tumorigenesis of human breast epithelial cellsDe novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndromeThe Rho-GTPase cdc42 regulates neural progenitor fate at the apical surfaceLis1 controls dynamics of neuronal filopodia and spines to impact synaptogenesis and social behaviourLis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization.LIS1 regulates osteoclast formation and function through its interactions with dynein/dynactin and Plekhm1p250GAP is a novel player in the Cdh1-APC/Smurf1 pathway of axon growth regulation.Myosin II motors and F-actin dynamics drive the coordinated movement of the centrosome and soma during CNS glial-guided neuronal migration.Leading process branch instability in Lis1+/- nonradially migrating interneuronsReelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation.LIS1 controls mitosis and mitotic spindle organization via the LIS1-NDEL1-dynein complex.Increased LIS1 expression affects human and mouse brain developmentDrebrin-mediated microtubule-actomyosin coupling steers cerebellar granule neuron nucleokinesis and migration pathway selectionNervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain.Coexpression of IQ-domain GTPase-activating protein 1 (IQGAP1) and Dishevelled (Dvl) is correlated with poor prognosis in non-small cell lung cancer.The trip of the tip: understanding the growth cone machinery.Control of cortical neuronal migration by glutamate and GABAIQGAP1 regulates NR2A signaling, spine density, and cognitive processes.A defect in the CLIP1 gene (CLIP-170) can cause autosomal recessive intellectual disabilityWhat disorders of cortical development tell us about the cortex: one plus one does not always make twoHooks and comets: The story of microtubule polarity orientation in the neuron.The role of Rho GTPase proteins in CNS neuronal migration.The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea.IQGAP1 and its binding proteins control diverse biological functions.Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane.Multiple proteins mediate IQGAP1-stimulated cell migration.Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signalingCytoskeleton in action: lissencephaly, a neuronal migration disorderCell biology in neuroscience: mechanisms of cell migration in the nervous system.Modulation of behavior by scaffolding proteins of the post-synaptic density.Pharmacogenetic analysis reveals a post-developmental role for Rac GTPases in Caenorhabditis elegans GABAergic neurotransmission.LIS1 Regulates Osteoclastogenesis through Modulation of M-SCF and RANKL Signaling Pathways and CDC42.
P2860
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P2860
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
description
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Januar 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/01/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/01/01)
@nl
наукова стаття, опублікована в січні 2006
@uk
مقالة علمية (نشرت عام 2006)
@ar
name
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@ast
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@en
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@nl
type
label
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@ast
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@en
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@nl
prefLabel
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@ast
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@en
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@nl
P2093
P3181
P356
P1433
P1476
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility
@en
P2093
Hajira B. Koeller
M. Elizabeth Ross
Paul C. Letourneau
Stanislav S. Kholmanskikh
Timothy Gomez
P2888
P3181
P356
10.1038/NN1619
P407
P577
2006-01-01T00:00:00Z