Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity
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Characterisation of a novel NR4A2 mutation in Parkinson's disease brainChronic Toxoplasma gondii in Nurr1-null heterozygous mice exacerbates elevated open field activityNur transcription factors in stress and addictionGenetic models of sensorimotor gating: relevance to neuropsychiatric disorders.Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspectsPrepulse inhibition and genetic mouse models of schizophrenia.Behavioral genetic contributions to the study of addiction-related amphetamine effects.Minireview: Nuclear hormone receptor 4A signaling: implications for metabolic disease.NR4A gene expression is dynamically regulated in the ventral tegmental area dopamine neurons and is related to expression of dopamine neurotransmission genes.The N-terminal region of Nurr1 (a.a 1-31) is essential for its efficient degradation by the ubiquitin proteasome pathway.Knockdown of Nurr1 in the rat hippocampus: implications to spatial discrimination learning and memory.Schizophrenia: do all roads lead to dopamine or is this where they start? Evidence from two epidemiologically informed developmental rodent models.Structure of distress call: implication for specificity and activation of dopaminergic system.Nurr1 regulates Top IIβ and functions in axon genesis of mesencephalic dopaminergic neuronsDopamine Agonists Exert Nurr1-inducing Effect in Peripheral Blood Mononuclear Cells of Patients with Parkinson's DiseaseNR4A2: effects of an "orphan" receptor on sustained attention in a schizophrenic populationNurr1 in Parkinson's disease and related disorders.Target identification for CNS diseases by transcriptional profiling.Etiopathogenesis of Parkinson disease: a new beginning?Altered gene expression in the dorsolateral prefrontal cortex of individuals with schizophrenia.Bdnf gene is a downstream target of Nurr1 transcription factor in rat midbrain neurons in vitro.The Stress-Responding miR-132-3p Shows Evolutionarily Conserved Pathway Interactions.Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant nurr1 mutant.The Transcription Factor NURR1 Exerts Concentration-Dependent Effects on Target Genes Mediating Distinct Biological Processes.Tyrosine hydroxylase-positive neurons intrinsic to the human striatum express the transcription factor Nurr1.Sensorimotor gating deficits in "two-hit" models of schizophrenia risk factors.Long 3'UTR of Nurr1 mRNAs is targeted by miRNAs in mesencephalic dopamine neurons.Stress affects dopaminergic signaling pathways in Drosophila melanogaster.Adult mice with reduced Nurr1 expression: an animal model for schizophrenia.Role of Nurr1 in the Generation and Differentiation of Dopaminergic Neurons from Stem Cells.Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency.Repeated immobilization stress increases nur77 expression in the bed nucleus of the stria terminalis.Molecular characterization and analysis of the porcine NURR1 gene.
P2860
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P2860
Nurr1-null heterozygous mice have reduced mesolimbic and mesocortical dopamine levels and increased stress-induced locomotor activity
description
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im Oktober 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/10/17)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/10/17)
@nl
наукова стаття, опублікована в жовтні 2002
@uk
مقالة علمية (نشرت في 17-10-2002)
@ar
name
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@ast
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@en
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@nl
type
label
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@ast
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@en
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@nl
prefLabel
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@ast
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@en
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@nl
P2093
P1476
Nurr1-null heterozygous mice h ...... ess-induced locomotor activity
@en
P2093
B K Lipska
J A Misler
V M Nikodem
P304
P356
10.1016/S0166-4328(02)00185-7
P407
P50
P577
2002-10-01T00:00:00Z