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Gene expression parallels synaptic excitability and plasticity changes in Alzheimer's diseaseMaintenance of postmitotic neuronal cell identityTreating Parkinson's disease in the 21st century: can stem cell transplantation compete?Efficient and biologically relevant consensus strategy for Parkinson's disease gene prioritization.Parkinson's disease as a result of agingLow dose bexarotene treatment rescues dopamine neurons and restores behavioral function in models of Parkinson's disease.Nuclear receptor unfulfilled regulates axonal guidance and cell identity of Drosophila mushroom body neurons.Age-related changes in dopamine signaling in Nurr1 deficient mice as a model of Parkinson's diseaseIdentification of NURR1 as a mediator of MIF signaling during chronic arthritis: effects on glucocorticoid-induced MKP1α-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons.Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons.The N-terminal region of Nurr1 (a.a 1-31) is essential for its efficient degradation by the ubiquitin proteasome pathway.Correlation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease.Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson's disease.NURR1 in Parkinson disease--from pathogenesis to therapeutic potential.A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C).The Nurr1 Activator 1,1-Bis(3'-Indolyl)-1-(p-Chlorophenyl)Methane Blocks Inflammatory Gene Expression in BV-2 Microglial Cells by Inhibiting Nuclear Factor κBKnockdown of Nurr1 in the rat hippocampus: implications to spatial discrimination learning and memory.Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's diseaseBasal ganglia dopamine loss due to defect in purine recyclingAlterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease.Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates.Conditional expression of Parkinson's disease-related mutant α-synuclein in the midbrain dopaminergic neurons causes progressive neurodegeneration and degradation of transcription factor nuclear receptor related 1Dopamine Agonists Exert Nurr1-inducing Effect in Peripheral Blood Mononuclear Cells of Patients with Parkinson's DiseaseNurr1-Based Therapies for Parkinson's Disease.Decreased NURR1 gene expression in patients with Parkinson's disease.Target identification for CNS diseases by transcriptional profiling.Etiopathogenesis of Parkinson disease: a new beginning?Gene regulation as a potential avenue for the treatment of neurodegenerative disorders.Loss of functional alpha-synuclein: a toxic event in Parkinson's disease?The prion hypothesis of Parkinson's disease.The FOXP2-Driven Network in Developmental Disorders and NeurodegenerationModulatory Role of Nurr1 Activation and Thrombin Inhibition in the Neuroprotective Effects of Dabigatran Etexilate in Rotenone-Induced Parkinson's Disease in Rats.New and emerging medical therapies in Parkinson's disease.Alpha-synuclein-induced oxidative stress correlates with altered superoxide dismutase and glutathione synthesis in human neuroblastoma SH-SY5Y cells.Molecular changes in the postmortem parkinsonian brain.Aging and Parkinson's disease: Different sides of the same coin?Nuclear receptors in neural stem/progenitor cell homeostasis.Moracenin D from Mori Cortex radicis protects SH-SY5Y cells against dopamine-induced cell death by regulating nurr1 and α-synuclein expression.Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant nurr1 mutant.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Nurr1 in Parkinson's disease and related disorders.
@en
type
label
Nurr1 in Parkinson's disease and related disorders.
@en
prefLabel
Nurr1 in Parkinson's disease and related disorders.
@en
P2093
P2860
P356
P1476
Nurr1 in Parkinson's disease and related disorders.
@en
P2093
Elliott J Mufson
Katie Kompoliti
Weidong Le
Yaping Chu
P2860
P304
P356
10.1002/CNE.20828
P407
P577
2006-01-01T00:00:00Z