The serum response factor coactivator myocardin is required for vascular smooth muscle development
about
Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype.Leiomodin 1, a new serum response factor-dependent target gene expressed preferentially in differentiated smooth muscle cellsMyocardin is sufficient for a smooth muscle-like contractile phenotypeMegakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cellsSRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cellsThe LIM protein leupaxin is enriched in smooth muscle and functions as an serum response factor cofactor to induce smooth muscle cell gene transcriptionMyocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain proteinMuscle-specific signaling mechanism that links actin dynamics to serum response factor.Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in miceMicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injuryModulation of adverse cardiac remodeling by STARS, a mediator of MEF2 signaling and SRF activityDual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodelingEndothelial Plasticity: Shifting Phenotypes through Force FeedbackMending broken hearts: cardiac development as a basis for adult heart regeneration and repairMyocardin Family Members Drive Formation of CaveolaemiR-1/133a clusters cooperatively specify the cardiomyogenic lineage by adjustment of myocardin levels during embryonic heart developmentA regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate.Origin and differentiation of vascular smooth muscle cellsRegulation of myosin light chain kinase and telokin expression in smooth muscle tissuesProtein tyrosine phosphatase-like A regulates myoblast proliferation and differentiation through MyoG and the cell cycling signaling pathwayMyocardin is a bifunctional switch for smooth versus skeletal muscle differentiationCIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophyMyocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in miceThe SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expressionModulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardinRestricted inactivation of serum response factor to the cardiovascular systemThymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin bindingER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specificationMyocardin is required for cardiomyocyte survival and maintenance of heart functionRequirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiationAcute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland functionMyocardin is differentially required for the development of smooth muscle cells and cardiomyocytesmicroRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart.TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity.Yap1 protein regulates vascular smooth muscle cell phenotypic switch by interaction with myocardin.Genes that confer the identity of the renin cell.Histone deacetylase activity selectively regulates notch-mediated smooth muscle differentiation in human vascular cells.Myocardin overexpression is sufficient for promoting the development of a mature smooth muscle cell-like phenotype from human embryonic stem cellsThe smooth muscle cell-restricted KCNMB1 ion channel subunit is a direct transcriptional target of serum response factor and myocardin.Local delivery of the KCa3.1 blocker, TRAM-34, prevents acute angioplasty-induced coronary smooth muscle phenotypic modulation and limits stenosis.
P2860
Q24292785-552CAFAC-4FD7-4A68-9E8B-34E75E5A17EBQ24299386-AB94B56D-02D0-4890-9EDD-F9A6D833A334Q24308846-CE35763E-ADF2-453E-9396-881F17CBDFB4Q24309401-D7478CE4-9BFD-4648-9D03-B27406A61286Q24309440-E9F4CB2D-E75D-4E4C-9CCB-76C40FDD3330Q24315644-335575DA-CFC6-4308-BED1-D46E5EE28D1FQ24319981-7D5EC2F5-8BDD-48D8-A0CC-11AEE6FC0A90Q24520637-4C69EC3D-8DBB-4D7E-9C82-524848C38B46Q24557452-9684F2C5-AC24-4C7C-A18B-BE061FACFBD5Q24647407-5191A064-0D8B-40FD-B127-ED1464EEAB78Q24673391-6B6CD748-5E17-4C41-B057-126899DABDD3Q24684909-BE8983A6-4525-4ECF-A9E6-D8EA189C5C29Q26767430-7319DBAF-E0DF-4C1F-8E42-C0E6B830D275Q26852506-2E7675C3-7AD4-4A73-9D1D-11603BD78B42Q27301856-66780480-0640-4906-899D-3935E3291E02Q27320478-9CEC5417-AA85-427B-89E5-DAC7DD531A89Q27863408-9B672935-2957-48B6-9FF1-6C059113C5CEQ28080750-71A315E8-8C85-497A-BFB1-76FC75E7C690Q28246127-90301305-27D5-42C4-BF79-31B7EEAEC2CEQ28505564-59450337-452D-41FE-8B48-409CF43BECA2Q28506521-CB86E38E-622C-4D4A-8E07-3EC0C2D5C583Q28506542-6952F8B9-27D1-4CB5-90FE-147754FF8EFFQ28506846-F8363BF0-6AB3-4D53-A511-2F9BF7528175Q28507680-8856AFCD-FDEA-4A65-BA3A-354D10050353Q28511489-B8DAC4A8-7226-4AC7-99E9-178DE5CB1189Q28512435-6E0A3718-636E-4FE4-8B14-1E8A8B8504B3Q28581191-0F5F1EA3-99F0-4798-9735-24A07BD9181AQ28587231-931FDC7B-016C-4454-9CAE-884307C8C186Q28588163-76611D39-0699-49C2-926E-F043F299274EQ28592747-98486F89-538E-4F75-BFF7-28BD8BE54763Q28767351-FE4F6556-B9C8-4427-9F71-13120ED6BA87Q29347238-E6FC4B7A-A57C-45DD-936D-72DE0E448D56Q30090181-70BACEEE-B63D-47B9-839E-656CEF5B0F03Q30419332-C2C99DE6-96F4-48CF-A3FE-3C17F5A33742Q30419759-3A764DB0-F2F3-44E8-A7D4-F3E1F31D4A4BQ30423667-3D228A9B-A2E1-40E2-9675-B4D0C7F61731Q30424133-E27327FB-9CA9-484C-9FD6-A9ECEFB901B4Q30425384-0C08ACDB-8547-4851-B443-25A8AFE57DCAQ30434082-9BEB00EA-CF9F-46C5-902A-E6AA68192C86Q30440082-249F0C87-A05E-4870-BE4B-F668FE619961
P2860
The serum response factor coactivator myocardin is required for vascular smooth muscle development
description
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2003
@ast
im August 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/08/05)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/08/05)
@nl
наукова стаття, опублікована в серпні 2003
@uk
name
The serum response factor coac ...... ular smooth muscle development
@ast
The serum response factor coac ...... ular smooth muscle development
@en
The serum response factor coac ...... ular smooth muscle development
@nl
type
label
The serum response factor coac ...... ular smooth muscle development
@ast
The serum response factor coac ...... ular smooth muscle development
@en
The serum response factor coac ...... ular smooth muscle development
@nl
prefLabel
The serum response factor coac ...... ular smooth muscle development
@ast
The serum response factor coac ...... ular smooth muscle development
@en
The serum response factor coac ...... ular smooth muscle development
@nl
P2093
P2860
P356
P1476
The serum response factor coac ...... ular smooth muscle development
@en
P2093
Da-Zhi Wang
Eric N. Olson
James A. Richardson
Zhigao Wang
P2860
P304
P356
10.1073/PNAS.1233635100
P407
P577
2003-08-05T00:00:00Z