Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development
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Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomesStimulation of retinoic acid production and growth by ubiquitously expressed alcohol dehydrogenase Adh3Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical applicationDynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear.Characterization of retinaldehyde dehydrogenase 3Mouse retinal dehydrogenase 4 (RALDH4), molecular cloning, cellular expression, and activity in 9-cis-retinoic acid biosynthesis in intact cellsMultiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytesGenetic evidence that retinaldehyde dehydrogenase Raldh1 (Aldh1a1) functions downstream of alcohol dehydrogenase Adh1 in metabolism of retinol to retinoic acidOpposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradationRetinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterningTargeted disruption of Aldh1a1 (Raldh1) provides evidence for a complex mechanism of retinoic acid synthesis in the developing retinaA newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatmentDistinct retinoid metabolic functions for alcohol dehydrogenase genes Adh1 and Adh4 in protection against vitamin A toxicity or deficiency revealed in double null mutant miceFunctions of Intracellular Retinoid Binding-Proteins.Evidence that the human gene for prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1).Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo.Physiological insights into all-trans-retinoic acid biosynthesis.Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism.ALDH1A3 mutations cause recessive anophthalmia and microphthalmia.Localization of retinaldehyde dehydrogenases and retinoid binding proteins to sustentacular cells, glia, Bowman's gland cells, and stroma: potential sites of retinoic acid synthesis in the postnatal rat olfactory organ.Signaling "cross-talk" is integrated by transcription factors in the development of the anterior segment in the eye.Regulation of retinoic acid synthetic enzymes by WT1 and HDAC inhibitors in 293 cells.Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases.New insights and changing paradigms in the regulation of vitamin A metabolism in development.Novel retinoic acid generating activities in the neural tube and heart identified by conditional rescue of Raldh2 null mutant mice.Cloning of monkey RALDH1 and characterization of retinoid metabolism in monkey kidney proximal tubule cells.Retinoic Acid Synthesis and Degradation.Differential regulation of the aldehyde dehydrogenase 1 gene in embryonic chick retina and liver.Retinoic acid signaling in the brain marks formation of optic projections, maturation of the dorsal telencephalon, and function of limbic sites.Retinoic acid derived from the fetal ovary initiates meiosis in mouse germ cells.Molecular signals regulating proliferation of stem and progenitor cells in mouse olfactory epithelium.Tissue distribution, ontogeny, and regulation of aldehyde dehydrogenase (Aldh) enzymes mRNA by prototypical microsomal enzyme inducers in mice.Novel splice-site and missense mutations in the ALDH1A3 gene underlying autosomal recessive anophthalmia/microphthalmia.Is retinoic acid genetic machinery a chordate innovation?
P2860
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P2860
Aldehyde dehydrogenase 6, a cytosolic retinaldehyde dehydrogenase prominently expressed in sensory neuroepithelia during development
description
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2000
@ast
im Dezember 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/12/29)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/12/29)
@nl
наукова стаття, опублікована в грудні 2000
@uk
name
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@ast
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@en
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@nl
type
label
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@ast
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@en
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@nl
prefLabel
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@ast
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@en
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@nl
P2093
P356
P1476
Aldehyde dehydrogenase 6, a cy ...... roepithelia during development
@en
P2093
P304
41210–41218
P356
10.1074/JBC.M007376200
P407
P577
2000-12-29T00:00:00Z