A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment
about
Retinoic acid synthesis and functions in early embryonic developmentALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cellsRetinoic acid synthesis and signaling during early organogenesisRetinoic acid regulation of the somitogenesis clockNon-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamilySignaling through retinoic acid receptors in cardiac development: Doing the right things at the right timesAldehyde dehydrogenases in cellular responses to oxidative/electrophilic stressLeukocyte homing, fate, and function are controlled by retinoic acidMechanisms of retinoic acid signalling and its roles in organ and limb developmentRole of Nuclear Receptors in Central Nervous System Development and Associated DiseasesEnzymatic Metabolism of Vitamin A in Developing Vertebrate EmbryosCrystal structure of human aldehyde dehydrogenase 1A3 complexed with NAD(+) and retinoic acidRetinoid content, visual responses, and ocular morphology are compromised in the retinas of mice lacking the retinol-binding protein receptor, STRA6Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear.Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytesRetinoic acid synthesis controlled by Raldh2 is required early for limb bud initiation and then later as a proximodistal signal during apical ectodermal ridge formationRDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ developmentOpposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradationRetinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterningRole of retinoic acid during forebrain development begins late when Raldh3 generates retinoic acid in the ventral subventricular zoneAldehyde dehydrogenase 1a1 is dispensable for stem cell function in the mouse hematopoietic and nervous systemsThe retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic developmentA missense mutation in ALDH1A3 causes isolated microphthalmia/anophthalmia in nine individuals from an inbred Muslim kindredRdh10 loss-of-function and perturbed retinoid signaling underlies the etiology of choanal atresia.Non-cell-autonomous retinoid signaling is crucial for renal development.Discovery of novel regulators of aldehyde dehydrogenase isoenzymesaldh7a1 regulates eye and limb development in zebrafish.Maternal residential atrazine exposure and risk for choanal atresia and stenosis in offspring.Aldehyde dehydrogenases: from eye crystallins to metabolic disease and cancer stem cellsRDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis.Molecular regulation of striatal development: a review.Retinaldehyde dehydrogenase 1 deficiency inhibits PPARγ-mediated bone loss and marrow adiposity.Analysis of thioester-containing proteins during the innate immune response of Drosophila melanogaster.Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout modelsRDH10 is the primary enzyme responsible for the first step of embryonic Vitamin A metabolism and retinoic acid synthesis.Hypertension and the fat-soluble vitamins A, D and E.Physiological insights into all-trans-retinoic acid biosynthesis.Involvement of retinol dehydrogenase 10 in embryonic patterning and rescue of its loss of function by maternal retinaldehyde treatment.Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.Pharmacological inhibition of ALDH1A in mice decreases all-trans retinoic acid concentrations in a tissue specific manner
P2860
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P2860
A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment
description
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2003
@ast
im November 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/11/25)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/11/25)
@nl
наукова стаття, опублікована в листопаді 2003
@uk
name
A newborn lethal defect due to ...... ternal retinoic acid treatment
@ast
A newborn lethal defect due to ...... ternal retinoic acid treatment
@en
A newborn lethal defect due to ...... ternal retinoic acid treatment
@nl
type
label
A newborn lethal defect due to ...... ternal retinoic acid treatment
@ast
A newborn lethal defect due to ...... ternal retinoic acid treatment
@en
A newborn lethal defect due to ...... ternal retinoic acid treatment
@nl
prefLabel
A newborn lethal defect due to ...... ternal retinoic acid treatment
@ast
A newborn lethal defect due to ...... ternal retinoic acid treatment
@en
A newborn lethal defect due to ...... ternal retinoic acid treatment
@nl
P2093
P2860
P50
P3181
P356
P1476
A newborn lethal defect due to ...... ternal retinoic acid treatment
@en
P2093
Jean-Marie Garnier
Manuel Mark
Norbert B. Ghyselinck
P2860
P304
14036–14041
P3181
P356
10.1073/PNAS.2336223100
P407
P577
2003-11-25T00:00:00Z