Varp interacts with Rab38 and functions as its potential effector
about
VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surfaceRole of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growthThe binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformationMultiple Roles of VARP in Endosomal Trafficking: Rabs, Retromer Components and R-SNARE VAMP7 Meet on VARPVarp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytesThe Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytesRab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells.BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriersStructure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes.Protein tyrosine phosphatase Meg2 dephosphorylates signal transducer and activator of transcription 3 and suppresses tumor growth in breast cancer.Multiple roles of the vesicular-SNARE TI-VAMP in post-Golgi and endosomal trafficking.Rab GEFs and GAPs.GABARAPL1 negatively regulates Wnt/β-catenin signaling by mediating Dvl2 degradation through the autophagy pathway.Rab9A is required for delivery of cargo from recycling endosomes to melanosomes.Rab40C is a novel Varp-binding protein that promotes proteasomal degradation of Varp in melanocytes.Rewiring a Rab regulatory network reveals a possible inhibitory role for the vesicle tether, Uso1.HPS1:HPS4 exchange GTP for GDP on RAB32 and RAB38
P2860
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P2860
Varp interacts with Rab38 and functions as its potential effector
description
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Juli 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/07/18)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/07/18)
@nl
наукова стаття, опублікована в липні 2008
@uk
مقالة علمية (نشرت في 18-7-2008)
@ar
name
Varp interacts with Rab38 and functions as its potential effector
@ast
Varp interacts with Rab38 and functions as its potential effector
@en
Varp interacts with Rab38 and functions as its potential effector
@nl
type
label
Varp interacts with Rab38 and functions as its potential effector
@ast
Varp interacts with Rab38 and functions as its potential effector
@en
Varp interacts with Rab38 and functions as its potential effector
@nl
prefLabel
Varp interacts with Rab38 and functions as its potential effector
@ast
Varp interacts with Rab38 and functions as its potential effector
@en
Varp interacts with Rab38 and functions as its potential effector
@nl
P2093
P3181
P1476
Varp interacts with Rab38 and functions as its potential effector
@en
P2093
Fangli Ren
Haiwei Zhang
Xiaoning Zhang
Xinjun Zhang
Yinyin Wang
Yonggong Zhai
Zhijie Chang
P304
P3181
P356
10.1016/J.BBRC.2008.05.017
P407
P577
2008-07-18T00:00:00Z