Knockout of PKC alpha enhances insulin signaling through PI3K
about
Phosphorylation of Ser357 of rat insulin receptor substrate-1 mediates adverse effects of protein kinase C-delta on insulin action in skeletal muscle cellsSyk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunityRegulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2PKCalpha regulates platelet granule secretion and thrombus formation in miceCholecystokinin facilitates glutamate release by increasing the number of readily releasable vesicles and releasing probability.Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylationThe Complex Roles of Mechanistic Target of Rapamycin in Adipocytes and Beyond.Disease Phenotypes in a Mouse Model of RNA Toxicity Are Independent of Protein Kinase Cα and Protein Kinase CβSystems genetics of metabolism: the use of the BXD murine reference panel for multiscalar integration of traitsImmunolocalization of protein kinase C isoenzymes alpha, beta I, beta II, delta, and epsilon in mouse kidney.RNAi screening for kinases and phosphatases identifies FoxO regulatorsPodocytic PKC-alpha is regulated in murine and human diabetes and mediates nephrin endocytosis.Protein kinase C is a calcium sensor for presynaptic short-term plasticity.Synergy analysis reveals association between insulin signaling and desmoplakin expression in palmitate treated HepG2 cellsOverexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin actionAdenoviral gene transfer of PLD1-D4 enhances insulin sensitivity in mice by disrupting phospholipase D1 interaction with PED/PEA-15.Altered morphology and function of the lacrimal functional unit in protein kinase C{alpha} knockout mice.PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans.Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo.Insulin-producing surrogate β-cells from embryonic stem cells: are we there yet?Protein kinase Cδ promotes proliferation and induces malignant transformation in skeletal muscleIsozyme-specific effects of protein kinase C in pain modulation.PKC{alpha} is essential for the proper activation and termination of rod bipolar cell responseGroup 1B phospholipase A2-mediated lysophospholipid absorption directly contributes to postprandial hyperglycemia.The role of protein kinase C-alpha in hematologic malignancies.Specific protein kinase C isoforms as transducers and modulators of insulin signalingDiacylglycerol kinase δ modulates Akt phosphorylation through pleckstrin homology domain leucine-rich repeat protein phosphatase 2 (PHLPP2)Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes.Adaptive regulation maintains posttetanic potentiation at cerebellar granule cell synapses in the absence of calcium-dependent PKCCalcium-dependent isoforms of protein kinase C mediate glycine-induced synaptic enhancement at the calyx of Held.Regulation of insulin receptor substrate-1 by mTORC2 (mammalian target of rapamycin complex 2)Metabolic functions of atypical protein kinase C: "good" and "bad" as defined by nutritional status.PRKCA: a positional candidate gene for body mass index and asthma.Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis.Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's diseaseProtein kinase Calpha: disease regulator and therapeutic target.Sodium acetate decreases phosphorylation of hormone sensitive lipase in isoproterenol-stimulated 3T3-L1 mature adipocytes.Mammalian TOR signaling to the AGC kinases.The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity.PKCβ: Expanding role in hepatic adaptation of cholesterol homeostasis to dietary fat/cholesterol.
P2860
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P2860
Knockout of PKC alpha enhances insulin signaling through PI3K
description
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
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im April 2002 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2002/04/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/04/01)
@nl
наукова стаття, опублікована у квітні 2002
@uk
مقالة علمية (نشرت في أبريل 2002)
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name
Knockout of PKC alpha enhances insulin signaling through PI3K
@ast
Knockout of PKC alpha enhances insulin signaling through PI3K
@en
Knockout of PKC alpha enhances insulin signaling through PI3K
@nl
type
label
Knockout of PKC alpha enhances insulin signaling through PI3K
@ast
Knockout of PKC alpha enhances insulin signaling through PI3K
@en
Knockout of PKC alpha enhances insulin signaling through PI3K
@nl
prefLabel
Knockout of PKC alpha enhances insulin signaling through PI3K
@ast
Knockout of PKC alpha enhances insulin signaling through PI3K
@en
Knockout of PKC alpha enhances insulin signaling through PI3K
@nl
P2093
P3181
P1476
Knockout of PKC alpha enhances insulin signaling through PI3K
@en
P2093
Gautam Bandyopadhyay
Markus Plomann
Mary L. Standaert
Michael Leitges
Michael Letiges
Mini P. Sajan
Robert V. Farese
Yoshinori Kanoh
P304
P3181
P356
10.1210/ME.16.4.847
10.1210/MEND.16.4.0809
P577
2002-04-01T00:00:00Z