BRCA2 is required for neurogenesis and suppression of medulloblastoma
about
Molecular pathogenesis and clinical management of Fanconi anemiaRequirement of mouse BCCIP for neural development and progenitor proliferationBrca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesisThe genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1In vivo importance of homologous recombination DNA repair for mouse neural stem and progenitor cellsEvolutionary genomics of human intellectual disabilityPot1a prevents telomere dysfunction and ATM-dependent neuronal loss.Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degenerationAltered methylation of the DNA repair gene MGMT is associated with neural tube defects.Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.Disseminated Medulloblastoma in a Child with Germline BRCA2 6174delT Mutation and without Fanconi AnemiaFanconi DNA repair pathway is required for survival and long-term maintenance of neural progenitors.Fanconi anemia-D1 due to homozygosity for the BRCA2 gene Cypriot founder mutation: A case reportCerebellum Development and Tumorigenesis: A p53-Centric Perspective.DNA double-strand break repair and development.Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma.Cross-species genomic and epigenomic landscape of retinoblastoma.DNA strand breaks, neurodegeneration and aging in the brain.Mouse models of DNA double-strand break repair and neurological diseaseGenetic causes of microcephaly and lessons for neuronal development.Transcriptional regulation of neuronal differentiation: the epigenetic layer of complexity.Genetically engineered mouse models of brain cancer and the promise of preclinical testingA population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity.Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.Loss of Rad51c leads to embryonic lethality and modulation of Trp53-dependent tumorigenesis in mice.DNA repair deficiency and neurological disease.Immunological considerations of modern animal models of malignant primary brain tumors.To live or to die: a matter of processing damaged DNA termini in neurons.Review: personalized mice: modelling the molecular heterogeneity of medulloblastoma.Matching mice to malignancy: molecular subgroups and models of medulloblastoma.What underlies the diversity of brain tumors?Proteomic Analysis of Mouse Cortex Postsynaptic Density following Neonatal Brain Hypoxia-Ischemia.Fanconi anemia: correlating central nervous system malformations and genetic complementation groups.ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.Exploration of Involved Key Genes and Signaling Diversity in Brain Tumors.Medulloblastoma: experimental models and reality.BCCIP suppresses tumor initiation but is required for tumor progressionLoss of the chromatin regulator MRG15 limits neural stem/progenitor cell proliferation via increased expression of the p21 Cdk inhibitor.
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P2860
BRCA2 is required for neurogenesis and suppression of medulloblastoma
description
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Juni 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/06/06)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/06/06)
@nl
наукова стаття, опублікована в червні 2007
@uk
مقالة علمية (نشرت في 6-6-2007)
@ar
name
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@ast
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@en
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@nl
type
label
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@ast
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@en
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@nl
prefLabel
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@ast
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@en
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@nl
P2093
P2860
P921
P356
P1433
P1476
BRCA2 is required for neurogenesis and suppression of medulloblastoma
@en
P2093
Jayne Lamont
Peter J. McKinnon
Youngsoo Lee
P2860
P304
P356
10.1038/SJ.EMBOJ.7601703
P407
P577
2007-06-06T00:00:00Z