The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium
about
Single-cell dissection of transcriptional heterogeneity in human colon tumorsStomach development, stem cells and diseaseUnderstanding epithelial homeostasis in the intestine: An old battlefield of ideas, recent breakthroughs and remaining controversiesEpithelial IL-18 Equilibrium Controls Barrier Function in Colitis.ETS-4 is a transcriptional regulator of life span in Caenorhabditis elegansDelta1 expression, cell cycle exit, and commitment to a specific secretory fate coincide within a few hours in the mouse intestinal stem cell systemDll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cellsConservation of transcription factor binding specificities across 600 million years of bilateria evolutionThe two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactionsAdult zebrafish intestine resection: a novel model of short bowel syndrome, adaptation, and intestinal stem cell regeneration.Runx1 is a tumor suppressor gene in the mouse gastrointestinal tract.Notch: architect, landscaper, and guardian of the intestine.Mouse conjunctival forniceal gene expression during postnatal development and its regulation by Kruppel-like factor 4.Combined NADPH oxidase 1 and interleukin 10 deficiency induces chronic endoplasmic reticulum stress and causes ulcerative colitis-like disease in miceLoss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer.Intestinal goblet cells and mucins in health and disease: recent insights and progress.Cdx2 levels modulate intestinal epithelium maturity and Paneth cell development.GATA factors regulate proliferation, differentiation, and gene expression in small intestine of mature miceRegulation of self-renewal and differentiation by the intestinal stem cell niche.Intestinal development and differentiation.Requirement of the epithelium-specific Ets transcription factor Spdef for mucous gland cell function in the gastric antrum.SPDEF inhibits prostate carcinogenesis by disrupting a positive feedback loop in regulation of the Foxm1 oncogene.Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP alleleDistinct ATOH1 and Neurog3 requirements define tuft cells as a new secretory cell type in the intestinal epithelium.Interleukin-13 (IL-13)/IL-13 receptor alpha1 (IL-13Ralpha1) signaling regulates intestinal epithelial cystic fibrosis transmembrane conductance regulator channel-dependent Cl- secretion.Loss of NHE8 expression impairs ocular surface function in miceVertebrate intestinal endoderm development.TGFβ signaling inhibits goblet cell differentiation via SPDEF in conjunctival epithelium.Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.Altered goblet cell differentiation and surface mucus properties in Hirschsprung disease.Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine.Generating intestinal tissue from stem cells: potential for research and therapy.Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration.Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.Geometry of the Gene Expression Space of Individual CellsAirway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation.The endoplasmic reticulum stress transducer OASIS is involved in the terminal differentiation of goblet cells in the large intestine.Ets2 regulates colonic stem cells and sensitivity to tumorigenesis.Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation.Recent advances in small bowel diseases: Part I.
P2860
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P2860
The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium
description
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Oktober 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/10/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/10/01)
@nl
наукова стаття, опублікована в жовтні 2009
@uk
مقالة علمية (نشرت في أكتوبر 2009)
@ar
name
The ets-domain transcription f ...... s in the intestinal epithelium
@ast
The ets-domain transcription f ...... s in the intestinal epithelium
@en
The ets-domain transcription f ...... s in the intestinal epithelium
@nl
type
label
The ets-domain transcription f ...... s in the intestinal epithelium
@ast
The ets-domain transcription f ...... s in the intestinal epithelium
@en
The ets-domain transcription f ...... s in the intestinal epithelium
@nl
prefLabel
The ets-domain transcription f ...... s in the intestinal epithelium
@ast
The ets-domain transcription f ...... s in the intestinal epithelium
@en
The ets-domain transcription f ...... s in the intestinal epithelium
@nl
P2093
P3181
P1433
P1476
The ets-domain transcription f ...... s in the intestinal epithelium
@en
P2093
Alex Gregorieff
Daniel E. Stange
Hans Clevers
Harry Begthel
Jeroen Korving
Pekka Kujala
Peter J. Peters
P304
1333–1345.e1-3
P3181
P356
10.1053/J.GASTRO.2009.06.044
P407
P577
2009-10-01T00:00:00Z