Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation
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SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactomeSH2B1beta adaptor is a key enhancer of RET tyrosine kinase signalingSH2B1β interacts with STAT3 and enhances fibroblast growth factor 1-induced gene expression during neuronal differentiationKinase activation through dimerization by human SH2-BClinical and biological characteristics of cervical neoplasias with FGFR3 mutation.Genetic insights into the mechanisms of Fgf signalingRegulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, LnkTyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B betaInterplay between cell migration and neurite outgrowth determines SH2B1β-enhanced neurite regeneration of differentiated PC12 cellsThe Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway.The receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling.SH2B1 regulation of energy balance, body weight, and glucose metabolism.YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling.The adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons.Gene disruption of Spred-2 causes dwarfism.MUC1 oncoprotein functions in activation of fibroblast growth factor receptor signalingNew function of the adaptor protein SH2B1 in brain-derived neurotrophic factor-induced neurite outgrowthHepatic SH2B1 and SH2B2 regulate liver lipid metabolism and VLDL secretion in miceIdentification of SH2B1β as a focal adhesion protein that regulates focal adhesion size and number.Neuronal SH2B1 is essential for controlling energy and glucose homeostasis.Adapter protein SH2-Bbeta stimulates actin-based motility of Listeria monocytogenes in a vasodilator-stimulated phosphoprotein (VASP)-dependent fashion.Constitutive activation of MEK1 in chondrocytes causes Stat1-independent achondroplasia-like dwarfism and rescues the Fgfr3-deficient mouse phenotypeGrb10 and Grb14: enigmatic regulators of insulin action--and more?Adapter protein SH2B1beta cross-links actin filaments and regulates actin cytoskeletonDisruption of the SH2-B gene causes age-dependent insulin resistance and glucose intoleranceInputs and outputs of insulin receptor.The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation.Adapter protein SH2-B beta undergoes nucleocytoplasmic shuttling: implications for nerve growth factor induction of neuronal differentiation.A novel interaction between fibroblast growth factor receptor 3 and the p85 subunit of phosphoinositide 3-kinase: activation-dependent regulation of ERK by p85 in multiple myeloma cells.Constitutively activated FGFR3 mutants signal through PLCgamma-dependent and -independent pathways for hematopoietic transformation.Phosphorylation of the Unique C-terminal Tail of the Alpha Isoform of the Scaffold Protein SH2B1 Controls the Ability of SH2B1alpha to Enhance Nerve Growth Factor Function.
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Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation
description
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
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artículu científicu espublizáu en 2002
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im Mai 2002 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2002/05/03)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/05/03)
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наукова стаття, опублікована в травні 2002
@uk
name
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@ast
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@en
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@nl
type
label
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@ast
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@en
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@nl
prefLabel
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@ast
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@en
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@nl
P2093
P2860
P356
P1476
Interaction of fibroblast grow ...... -B. A role in STAT5 activation
@en
P2093
Ching S. Wang
Daniel J. Donoghue
Monica Kong
P2860
P304
15962–15970
P356
10.1074/JBC.M102777200
P407
P577
2002-05-03T00:00:00Z