Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins
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Role and expression of FRS2 and FRS3 in prostate cancerIdentification of tyrosine residues in constitutively activated fibroblast growth factor receptor 3 involved in mitogenesis, Stat activation, and phosphatidylinositol 3-kinase activationThe Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cellsFibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblasts8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathwaysDocking protein FRS2 links the protein tyrosine kinase RET and its oncogenic forms with the mitogen-activated protein kinase signaling cascadeFRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptorsStimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteinsA unique autophosphorylation site on Tie2/Tek mediates Dok-R phosphotyrosine binding domain binding and functionStructural basis of SNT PTB domain interactions with distinct neurotrophic receptorsGenetic insights into the mechanisms of Fgf signalingA novel type I fibroblast growth factor receptor activates mitogenic signaling in the absence of detectable tyrosine phosphorylation of FRS2Association of atypical protein kinase C isotypes with the docker protein FRS2 in fibroblast growth factor signalingAssociation of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partnerThe signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiationCharacterization of FIM-FGFR1, the fusion product of the myeloproliferative disorder-associated t(8;13) translocationSpecific inhibition of FGF-induced MAPK activation by the receptor-like protein tyrosine phosphatase LARTyrosine phosphorylation of the Bcl-2-associated protein BNIP-2 by fibroblast growth factor receptor-1 prevents its binding to Cdc42GAP and Cdc42Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transductionMultiple effector domains within SNT1 coordinate ERK activation and neuronal differentiation of PC12 cellsFibroblast growth factor signaling in Caenorhabditis elegansSrc activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinasesXenopus FRS2 is involved in early embryogenesis in cooperation with the Src family kinase Laloo.Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasiaALK activation induces Shc and FRS2 recruitment: Signaling and phenotypic outcomes in PC12 cells differentiationFRS2 via fibroblast growth factor receptor 1 is required for platelet-derived growth factor receptor beta-mediated regulation of vascular smooth muscle marker gene expressionPDGF-BB-mediated activation of p42(MAPK) is independent of PDGF beta-receptor tyrosine phosphorylationIndependent SH2-binding sites mediate interaction of Dok-related protein with RasGTPase-activating protein and NckFrs2α enhances fibroblast growth factor-mediated survival and differentiation in lens developmentInteraction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activationMolecular networks in FGF signaling: flotillin-1 and cbl-associated protein compete for the binding to fibroblast growth factor receptor substrate 2Novel phosphotyrosine targets of FGFR2IIIb signaling.Caenorhabditis elegans fibroblast growth factor receptor signaling can occur independently of the multi-substrate adaptor FRS2.Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis.FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts.Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4.The Fibroblast Growth Factor signaling pathwayUnique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways.PTB or not PTB -- that is the question.Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms.
P2860
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P248
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P2860
Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins
description
1998 nî lūn-bûn
@nan
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Novel recognition motif on fib ...... vation of SNT adapter proteins
@ast
Novel recognition motif on fib ...... vation of SNT adapter proteins
@en
Novel recognition motif on fib ...... vation of SNT adapter proteins
@en-gb
Novel recognition motif on fib ...... vation of SNT adapter proteins
@nl
type
label
Novel recognition motif on fib ...... vation of SNT adapter proteins
@ast
Novel recognition motif on fib ...... vation of SNT adapter proteins
@en
Novel recognition motif on fib ...... vation of SNT adapter proteins
@en-gb
Novel recognition motif on fib ...... vation of SNT adapter proteins
@nl
prefLabel
Novel recognition motif on fib ...... vation of SNT adapter proteins
@ast
Novel recognition motif on fib ...... vation of SNT adapter proteins
@en
Novel recognition motif on fib ...... vation of SNT adapter proteins
@en-gb
Novel recognition motif on fib ...... vation of SNT adapter proteins
@nl
P2093
P356
P1476
Novel recognition motif on fib ...... vation of SNT adapter proteins
@en
P2093
P304
P356
10.1074/JBC.273.29.17987
P407
P577
1998-07-17T00:00:00Z