Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice
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HNF-1beta regulates transcription of the PKD modifier gene Kif12ARPKD and early manifestations of ADPKD: the original polycystic kidney disease and phenocopiesSingle-gene causes of congenital anomalies of the kidney and urinary tract (CAKUT) in humansPolycystic liver diseases: advanced insights into the molecular mechanismsHeat-shock mediated overexpression of HNF1β mutations has differential effects on gene expression in the Xenopus pronephric kidneySnail activation disrupts tissue homeostasis and induces fibrosis in the adult kidneyGlomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expressionPolycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseasesThe role for HNF-1beta-targeted collectrin in maintenance of primary cilia and cell polarity in collecting duct cells.Atlas of gene expression in the developing kidney at microanatomic resolution.Aberrant planar cell polarity induced by urinary tract obstruction.Autophagy is a component of epithelial cell fate in obstructive uropathy.Identifying tissue-selective transcription factor binding sites in vertebrate promotersKidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathwayTissue-specific regulation of the mouse Pkhd1 (ARPKD) gene promoterGlomerulocystic kidney diseaseMutations in multiple PKD genes may explain early and severe polycystic kidney disease.Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian kidney.HNF1B mutations associate with hypomagnesemia and renal magnesium wasting.Hnf-1β transcription factor is an early hif-1α-independent marker of epithelial hypoxia and controls renal repair.Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia.HNF1B and PAX2 mutations are a common cause of renal hypodysplasia in the CKiD cohort.Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.Genetic basis of prune belly syndrome: screening for HNF1β gene.Transcription Factor Hepatocyte Nuclear Factor-1β (HNF-1β) Regulates MicroRNA-200 Expression through a Long Noncoding RNAMutations of HNF-1beta inhibit epithelial morphogenesis through dysregulation of SOCS-3.LRP5 variants may contribute to ADPKDGenetic contribution and associated pathophysiology in end-stage renal diseasemiR-17~92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease.Zyxin regulates migration of renal epithelial cells through activation of hepatocyte nuclear factor-1βGlis3 is associated with primary cilia and Wwtr1/TAZ and implicated in polycystic kidney disease.Mutations in PCBD1 cause hypomagnesemia and renal magnesium wasting.Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4alpha and HNF1beta in a pancreatic beta-cell line.Loss of transcriptional activation of the potassium channel Kir5.1 by HNF1β drives autosomal dominant tubulointerstitial kidney disease.Genetics of Congenital Anomalies of the Kidney and Urinary Tract: The Current State of Play.Genetics of vesicoureteral reflux and congenital anomalies of the kidney and urinary tract.A classification of ductal plate malformations based on distinct pathogenic mechanisms of biliary dysmorphogenesis.Transcription Factor Hepatocyte Nuclear Factor-1β Regulates Renal Cholesterol Metabolism.Genetic basis of human congenital anomalies of the kidney and urinary tract.
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P2860
Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice
description
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im März 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/03/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/03/01)
@nl
наукова стаття, опублікована в березні 2004
@uk
مقالة علمية (نشرت في مارس 2004)
@ar
name
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@ast
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@en
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@nl
type
label
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@ast
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@en
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@nl
prefLabel
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@ast
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@en
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@nl
P2093
P2860
P921
P356
P1476
Mutation of hepatocyte nuclear ...... d produces renal cysts in mice
@en
P2093
Angus M. Sinclair
Brian T. McNally
Peter Igarashi
Stefan Somlo
Thomas Hiesberger
Xinli Shao
P2860
P304
P356
10.1172/JCI20083
P407
P577
2004-03-01T00:00:00Z