Phospholamban ablation and compensatory responses in the mammalian heart
about
A micropeptide encoded by a putative long noncoding RNA regulates muscle performanceThe human phospholamban Arg14-deletion mutant localizes to plasma membrane and interacts with the Na/K-ATPaseInfluence of a constitutive increase in myofilament Ca(2+)-sensitivity on Ca(2+)-fluxes and contraction of mouse heart ventricular myocytesCardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylationLong-term rescue of a familial hypertrophic cardiomyopathy caused by a mutation in the thin filament protein, tropomyosin, via modulation of a calcium cycling protein.Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice.Neuronal nitric oxide synthase signaling within cardiac myocytes targets phospholamban.Induced overexpression of phospholemman S68E mutant improves cardiac contractility and mortality after ischemia-reperfusion.Phospholamban ablation rescues the enhanced propensity to arrhythmias of mice with CaMKII-constitutive phosphorylation of RyR2 at site S2814.
P2860
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P2860
Phospholamban ablation and compensatory responses in the mammalian heart
description
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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artículu científicu espublizáu en 1998
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im September 1998 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 1998/09/16)
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vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/09/16)
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наукова стаття, опублікована у вересні 1998
@uk
مقالة علمية (نشرت في 16-9-1998)
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name
Phospholamban ablation and compensatory responses in the mammalian heart
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Phospholamban ablation and compensatory responses in the mammalian heart
@en
Phospholamban ablation and compensatory responses in the mammalian heart
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type
label
Phospholamban ablation and compensatory responses in the mammalian heart
@ast
Phospholamban ablation and compensatory responses in the mammalian heart
@en
Phospholamban ablation and compensatory responses in the mammalian heart
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prefLabel
Phospholamban ablation and compensatory responses in the mammalian heart
@ast
Phospholamban ablation and compensatory responses in the mammalian heart
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Phospholamban ablation and compensatory responses in the mammalian heart
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P2093
P1476
Phospholamban ablation and compensatory responses in the mammalian heart
@en
P2093
P407
P577
1998-09-16T00:00:00Z