Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation
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CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 functionArginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptor-mediated gene transcription and breast cancer cell growthMediator-dependent nuclear receptor functionThe Mediator complex and transcription regulationAn Experimental Analysis of the Molecular Effects of Trastuzumab (Herceptin) and Fulvestrant (Falsodex), as Single Agents or in Combination, on Human HR+/HER2+ Breast Cancer Cell Lines and Mouse Tumor XenograftsAblation of coactivator Med1 switches the cell fate of dental epithelia to that generating hair.LXXLL peptide converts transportan 10 to a potent inducer of apoptosis in breast cancer cells.Mediator and human diseaseA muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolismCross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells.Estrogen receptor coregulators and pioneer factors: the orchestrators of mammary gland cell fate and development.Med1 regulates meiotic progression during spermatogenesis in miceMinireview: estrogen receptor-initiated mechanisms causal to mammalian reproductive behaviors.Silencing MED1 sensitizes breast cancer cells to pure anti-estrogen fulvestrant in vitro and in vivo.Structural guided scaffold phage display libraries as a source of bio-therapeutics.Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter.MicroRNA 146 (Mir146) modulates spermatogonial differentiation by retinoic acid in mice.Maintaining ancient organelles: mitochondrial biogenesis and maturation.Mediator subunits MED1 and MED24 cooperatively contribute to pubertal mammary gland development and growth of breast carcinoma cells.Coactivator MED1 ablation in keratinocytes results in hair-cycling defects and epidermal alterations.Physical association of the WC-1 photoreceptor and the histone acetyltransferase NGF-1 is required for blue light signal transduction in Neurospora crassaThe transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signalsRegulation of metabolism by the Mediator complex.The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation.Molecular regulators of pubertal mammary gland development.On the border of the homeotic function: re-evaluating the controversial role of cofactor-recruiting motifs: the role of cofactor-recruiting motifs in conferring Hox evolutionary flexibility may critically depend on the protein environment.ftz evolution: findings, hypotheses and speculations (response to DOI 10.1002/bies.201100019).Relationship between Structure and Conformational Change of the Vitamin D Receptor Ligand Binding Domain in 1α,25-Dihydroxyvitamin D3 Signaling.Mediator 1 contributes to enamel mineralization as a coactivator for Notch1 signaling and stimulates transcription of the alkaline phosphatase gene.Pubertal Mammary Gland Development: Elucidation of In Vivo Morphogenesis Using Murine Models.Cohesin is required for expression of the estrogen receptor-alpha (ESR1) gene.HER2-Driven Breast Tumorigenesis Relies upon Interactions of the Estrogen Receptor with Coactivator MED1.Overcoming Tamoxifen Resistance of Human Breast Cancer by Targeted Gene Silencing Using Multifunctional pRNA Nanoparticles.PHYTOCHROME AND FLOWERING TIME1/MEDIATOR25 Regulates Lateral Root Formation via Auxin Signaling in Arabidopsis.The mediator complex in genomic and non-genomic signaling in cancer.
P2860
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P2860
Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation
description
2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2010
@ast
im April 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/04/13)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/04/13)
@nl
наукова стаття, опублікована у квітні 2010
@uk
name
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@ast
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@en
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@nl
type
label
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@ast
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@en
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@nl
prefLabel
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@ast
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@en
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@nl
P2093
P2860
P356
P1476
Key roles for MED1 LxxLL motif ...... d luminal-cell differentiation
@en
P2093
Mitsuhiro Ito
Pingping Jiang
Qiuping Hu
Robert G Roeder
Sohaib Khan
Xiaoting Zhang
P2860
P304
P356
10.1073/PNAS.1001814107
P407
P577
2010-03-29T00:00:00Z