The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation.
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HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxiaSubunit architecture and functional modular rearrangements of the transcriptional mediator complexMultiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loopsCCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 functionMED12 mutations link intellectual disability syndromes with dysregulated GLI3-dependent Sonic Hedgehog signalingHigh mobility group protein 1: A collaborator in nucleosome dynamics and estrogen-responsive gene expressionWhat's new in estrogen receptor action in the female reproductive tractImportance of Mediator complex in the regulation and integration of diverse signaling pathways in plantsMediator kinase module and human tumorigenesisContributions of in vitro transcription to the understanding of human RNA polymerase III transcriptionDynamic integration of splicing within gene regulatory pathwaysInvestigating the transcriptional control of cardiovascular developmentMediator-dependent nuclear receptor functionDrosophila melanogaster Hox transcription factors access the RNA polymerase II machinery through direct homeodomain binding to a conserved motif of mediator subunit Med19Molecular Dynamics of "Fuzzy" Transcriptional Activator-Coactivator InteractionsThe evolutionarily conserved mediator subunit MDT-15/MED15 links protective innate immune responses and xenobiotic detoxificationMediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilizationArchitecture of the Mediator head moduleStructural Basis for LMO2-Driven Recruitment of the SCL:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional TargetsDifferential Properties of Transcriptional Complexes Formed by the CoREST FamilySrb5/Med18-mediated termination of transcription is dependent on gene loopingMediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16The selection and function of cell type-specific enhancersRegulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1The Mediator Kinase Module Restrains Epidermal Growth Factor Receptor Signaling and Represses Vulval Cell Fate Specification in Caenorhabditis elegansMediator MED15 modulates transforming growth factor beta (TGFβ)/Smad signaling and breast cancer cell metastasisThe Mediator complex and transcription regulationNovel oxytocin gene expression in the hindbrain is induced by alcohol exposure: transgenic zebrafish enable visualization of sensitive neuronsThe transcriptional mediator component Med12 is required for hindbrain boundary formationA cardiac microRNA governs systemic energy homeostasis by regulation of MED13Functional interplay between Mediator and TFIIB in preinitiation complex assembly in relation to promoter architectureCharacterization of ERM transactivation domain binding to the ACID/PTOV domain of the Mediator subunit MED25RNA polymerase structure, function, regulation, dynamics, fidelity, and roles in gene expressionFgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and TemplateSelective inhibition of tumor oncogenes by disruption of super-enhancersMaster transcription factors and mediator establish super-enhancers at key cell identity genesProteome-wide detection of Abl1 SH3-binding peptides by integrating computational prediction and peptide microarray.A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31.MultiBac complexomics.
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The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 October 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The metazoan Mediator co-activ ...... or transcriptional regulation.
@en
The metazoan Mediator co-activ ...... or transcriptional regulation.
@nl
type
label
The metazoan Mediator co-activ ...... or transcriptional regulation.
@en
The metazoan Mediator co-activ ...... or transcriptional regulation.
@nl
prefLabel
The metazoan Mediator co-activ ...... or transcriptional regulation.
@en
The metazoan Mediator co-activ ...... or transcriptional regulation.
@nl
P2860
P356
P1476
The metazoan Mediator co-activ ...... or transcriptional regulation.
@en
P2093
Robert G Roeder
Sohail Malik
P2860
P2888
P304
P356
10.1038/NRG2901
P577
2010-10-13T00:00:00Z