Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase
about
Posttranscriptional RNA Modifications: playing metabolic games in a cell's chemical LegolandInvestigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as InhibitorHot-spot analysis to dissect the functional protein-protein interface of a tRNA-modifying enzymeCharacterization of the human tRNA-guanine transglycosylase: confirmation of the heterodimeric subunit structureQueuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidationIdentification of Plasmodium falciparum apicoplast-targeted tRNA-guanine transglycosylase and its potential inhibitors using comparative genomics, molecular modelling, docking and simulation studiesIn vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis.Biosynthesis of pyrrolopyrimidines.Transfer RNA modifications and genes for modifying enzymes in Arabidopsis thaliana.A complete landscape of post-transcriptional modifications in mammalian mitochondrial tRNAs.Plant, animal, and fungal micronutrient queuosine is salvaged by members of the DUF2419 protein family.The queuine micronutrient: charting a course from microbe to man.Transfer RNA modifications: nature's combinatorial chemistry playground.Queuosine modification of tRNA: its divergent role in cellular machinery.Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease.Evolution of eukaryal tRNA-guanine transglycosylase: insight gained from the heterocyclic substrate recognition by the wild-type and mutant human and Escherichia coli tRNA-guanine transglycosylases.Deazaguanine derivatives, examples of crosstalk between RNA and DNA modification pathways.tRNA dynamics between the nucleus, cytoplasm and mitochondrial surface: Location, location, location.The mitochondrial epitranscriptome: the roles of RNA modifications in mitochondrial translation and human disease.Retrograde nuclear transport from the cytoplasm is required for tRNATyr maturation in T. brucei.QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr)
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P2860
Queuosine formation in eukaryotic tRNA occurs via a mitochondria-localized heteromeric transglycosylase
description
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2009
@ast
im Juli 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/07/03)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/07/03)
@nl
наукова стаття, опублікована в липні 2009
@uk
name
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@ast
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@en
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@nl
type
label
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@ast
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@en
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@nl
prefLabel
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@ast
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@en
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@nl
P2093
P2860
P921
P356
P1476
Queuosine formation in eukaryo ...... d heteromeric transglycosylase
@en
P2093
Ismael Santa-Maria
Patti Hayes
Susumu Nishimura
P2860
P304
18218-18227
P356
10.1074/JBC.M109.002477
P407
P577
2009-05-04T00:00:00Z