Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphology
about
Mechanisms of action of glucagon-like peptide 1 in the pancreasCyclic AMP dynamics in the pancreatic β-cellPhosphodiesterase 3B is localized in caveolae and smooth ER in mouse hepatocytes and is important in the regulation of glucose and lipid metabolismSphingosine kinase 1-interacting protein is a novel regulator of glucose-stimulated insulin secretionExpression and regulation of cyclic nucleotide phosphodiesterases in human and rat pancreatic islets.Resveratrol and curcumin enhance pancreatic β-cell function by inhibiting phosphodiesterase activity.Linking nutritional regulation of Angptl4, Gpihbp1, and Lmf1 to lipoprotein lipase activity in rodent adipose tissue.Alterations in regulation of energy homeostasis in cyclic nucleotide phosphodiesterase 3B-null miceFrom PDE3B to the regulation of energy homeostasisCyclic nucleotide phosphodiesterase 3A-deficient mice as a model of female infertility.Targeting beta-cell cyclic 3'5' adenosine monophosphate for the development of novel drugs for treating type 2 diabetes mellitus. A review.Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterasesPhosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue.The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 releaseClinical and molecular genetics of the phosphodiesterases (PDEs).β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced HyperglycemiaPhosphodiesterase 3A binds to 14-3-3 proteins in response to PMA-induced phosphorylation of Ser428.Regulation of AMP-activated protein kinase by cAMP in adipocytes: roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis.A novel approach to assess insulin sensitivity reveals no increased insulin sensitivity in mice with a dominant-negative mutant hepatocyte nuclear factor-1alpha.RNA-binding protein CUGBP1 regulates insulin secretion via activation of phosphodiesterase 3B in mice.
P2860
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P2860
Beta-cell-targeted overexpression of phosphodiesterase 3B in mice causes impaired insulin secretion, glucose intolerance, and deranged islet morphology
description
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2004
@ast
im April 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/04/09)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/04/09)
@nl
наукова стаття, опублікована у квітні 2004
@uk
name
Beta-cell-targeted overexpress ...... and deranged islet morphology
@ast
Beta-cell-targeted overexpress ...... and deranged islet morphology
@en
Beta-cell-targeted overexpress ...... and deranged islet morphology
@nl
type
label
Beta-cell-targeted overexpress ...... and deranged islet morphology
@ast
Beta-cell-targeted overexpress ...... and deranged islet morphology
@en
Beta-cell-targeted overexpress ...... and deranged islet morphology
@nl
prefLabel
Beta-cell-targeted overexpress ...... and deranged islet morphology
@ast
Beta-cell-targeted overexpress ...... and deranged islet morphology
@en
Beta-cell-targeted overexpress ...... and deranged islet morphology
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Beta-cell-targeted overexpress ...... and deranged islet morphology
@en
P2093
Eva Degerman
Frank Sundler
Linda Härndahl
Nils Wierup
Sven Enerbäck
Vincent C. Manganiello
P2860
P304
15214–15222
P3181
P356
10.1074/JBC.M308952200
P407
P577
2004-04-09T00:00:00Z