Mechanism of action of tetanus and botulinum neurotoxins
about
Laboratory diagnostics of botulismCommon themes in microbial pathogenicity revisitedTetanusStimulation of NSF ATPase activity by alpha-SNAP is required for SNARE complex disassembly and exocytosisCurrent status and future directions of botulinum neurotoxins for targeting pain processingPharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive ToolsThe structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside bindingThe crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxinA novel subunit structure of Clostridium botulinum serotype D toxin complex with three extended armsStructure- and substrate-based inhibitor design for Clostridium botulinum neurotoxin serotype ASNAP-25 Substrate Peptide (Residues 180-183) Binds to but Bypasses Cleavage by Catalytically Active Clostridium botulinum Neurotoxin ESubstrate Binding Mode and Its Implication on Drug Design for Botulinum Neurotoxin AMode of VAMP substrate recognition and inhibition of Clostridium botulinum neurotoxin FStructural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin ABotulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassayProteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavageAtoxic derivative of botulinum neurotoxin A as a prototype molecular vehicle for targeted delivery to the neuronal cytoplasmDiversity and impact of prokaryotic toxins on aquatic environments: a reviewDetection of botulinum neurotoxin serotype B at sub mouse LD(50) levels by a sandwich immunoassay and its application to toxin detection in milkAn assay for botulinum toxin types A, B and F that requires both functional binding and catalytic activities within the neurotoxin.Substrates and controls for the quantitative detection of active botulinum neurotoxin in protease-containing samplesUltrastructural localization of the binding fragment of tetanus toxin in putative gamma-aminobutyric acidergic terminals in the intermediolateral cell column: a potential basis for sympathetic dysfunction in generalized tetanus.Development of a delivery vehicle for intracellular transport of botulinum neurotoxin antagonists.Epitope characterization and variable region sequence of f1-40, a high-affinity monoclonal antibody to botulinum neurotoxin type a (Hall strain).Investigations into small molecule non-peptidic inhibitors of the botulinum neurotoxins.Protective antigen-mediated antibody response against a heterologous protein produced in vivo by Bacillus anthracisAdenovirus F protein as a delivery vehicle for botulinum BLethal factor active-site mutations affect catalytic activity in vitro.Short-term benefit from oral vancomycin treatment of regressive-onset autism.How could SNARE proteins open a fusion pore?Pure botulinum neurotoxin is absorbed from the stomach and small intestine and produces peripheral neuromuscular blockade.Characterization of the antibody response to the receptor binding domain of botulinum neurotoxin serotypes A and E.The active site structure of tetanus neurotoxin resolved by multiple scattering analysis in X-Ray absorption spectroscopy.Therapeutic use of botulinum toxin in migraine: mechanisms of action.Small-molecule quinolinol inhibitor identified provides protection against BoNT/A in mice.Botulinum toxin: bioweapon & magic drugSensitive and quantitative detection of botulinum neurotoxin in neurons derived from mouse embryonic stem cells.Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1Neuronal targeting, internalization, and biological activity of a recombinant atoxic derivative of botulinum neurotoxin A.Random phage display-based screening of peptides that bind to botulinum neurotoxin binding protein, nontoxic nonhemagglutinin.
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P2860
Mechanism of action of tetanus and botulinum neurotoxins
description
1994 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
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im Juli 1994 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 1994/07/01)
@sk
vědecký článek publikovaný v roce 1994
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wetenschappelijk artikel (gepubliceerd op 1994/07/01)
@nl
наукова стаття, опублікована в липні 1994
@uk
مقالة علمية (نشرت في يوليو 1994)
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name
Mechanism of action of tetanus and botulinum neurotoxins
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Mechanism of action of tetanus and botulinum neurotoxins
@en
Mechanism of action of tetanus and botulinum neurotoxins
@nl
type
label
Mechanism of action of tetanus and botulinum neurotoxins
@ast
Mechanism of action of tetanus and botulinum neurotoxins
@en
Mechanism of action of tetanus and botulinum neurotoxins
@nl
prefLabel
Mechanism of action of tetanus and botulinum neurotoxins
@ast
Mechanism of action of tetanus and botulinum neurotoxins
@en
Mechanism of action of tetanus and botulinum neurotoxins
@nl
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P1476
Mechanism of action of tetanus and botulinum neurotoxins
@en
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C Montecucco
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P3181
P356
10.1111/J.1365-2958.1994.TB00396.X
P407
P577
1994-07-01T00:00:00Z