Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras - Wikidata - wikimedia - TriplyDB

Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras

Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras

http://www.wikidata.org/entity/Q28609649

about

Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4 Intracellular retention, degradation, and signaling of glycosylation-deficient FGFR2 and craniosynostosis syndrome-associated FGFR2C278F Developmentally regulated expression and localization of fibroblast growth factor receptors in the human muscle Pleiotropic features of syndromic craniosynostoses correlate with differential expression of fibroblast growth factor receptors 1 and 2 during human craniofacial development The protein kinase C pathway plays a central role in the fibroblast growth factor-stimulated expression and transactivation activity of Runx2 Transforming growth factor-beta3 (Tgf-beta3) down-regulates Tgf-beta3 receptor type I (Tbetar-I) during rescue of cranial sutures from osseous obliteration Developmental and Evolutionary Significance of the Zygomatic Bone Increased calvaria cell differentiation and bone matrix formation induced by fibroblast growth factor receptor 2 mutations in Apert syndrome Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation Characterization of membrane protein interactions in plasma membrane derived vesicles with quantitative imaging Förster resonance energy transfer Evidence for digenic inheritance in some cases of Antley-Bixler syndrome?Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer Gly369Cys mutation in mouse FGFR3 causes achondroplasia by affecting both chondrogenesis and osteogenesis TACE activation by MAPK-mediated regulation of cell surface dimerization and TIMP3 association.Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase.Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis.A point mutation in the extracellular domain of KIT promotes tumorigenesis of mast cells via ligand-independent auto-dimerization In vivo modulation of FGF biological activity alters cranial suture fate A comprehensive review of the genetic basis of cleft lip and palate Bent bone dysplasia-FGFR2 type, a distinct skeletal disorder, has deficient canonical FGF signaling.Loss of fibroblast growth factor receptor 2 ligand-binding specificity in Apert syndrome.Uncoupling fibroblast growth factor receptor 2 ligand binding specificity leads to Apert syndrome-like phenotypes.FGFR2 mutation in 46,XY sex reversal with craniosynostosis Signaling by fibroblast growth factors (FGF) and fibroblast growth factor receptor 2 (FGFR2)-activating mutations blocks mineralization and induces apoptosis in osteoblasts.Unliganded EphA3 dimerization promoted by the SAM domain.Understanding craniosynostosis as a growth disorder Beyond GWASs: illuminating the dark road from association to function Fibroblast growth factor receptor 3 interacts with and activates TGFβ-activated kinase 1 tyrosine phosphorylation and NFκB signaling in multiple myeloma and bladder cancer.Physical-chemical principles underlying RTK activation, and their implications for human disease.The Fgfr2 W290R mouse model of Crouzon syndrome.The cytoplasmic tyrosine kinase Pyk2 as a novel effector of fibroblast growth factor receptor 3 activation.Mutations causing achondroplasia and thanatophoric dysplasia alter bFGF-induced calcium signals in human diploid fibroblasts.Clues from Crouzon: Insights into the potential role of growth factors in the pathogenesis of myelinated retinal nerve fibers.Fibroblast growth factors and early hemopoietic cell development.FGFR3 dimer stabilization due to a single amino acid pathogenic mutation.Signaling by FGFR in disease Expression of fibroblast growth factor receptors (FGFR1, FGFR2, FGFR3) in the developing head and face.Dimerization of FGFR2 ligand-independent mutants Autocatalytic phosphorylation of FGFR2 ligand-independent mutants

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Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR)2 and FGFR2/Neu chimeras

http://www.wikidata.org/entity/Q28609649

description

1996 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 1996

@ast

im Juli 1996 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 1996/07/23)

@sk

vědecký článek publikovaný v roce 1996

@cs

wetenschappelijk artikel (gepubliceerd op 1996/07/23)

@nl

наукова стаття, опублікована в липні 1996

@uk

name

Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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type

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Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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prefLabel

Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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PNAS.93.15.7894

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Proceedings of the National Academy of Sciences of the United States of America

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Constitutive receptor activati ...... (FGFR)2 and FGFR2/Neu chimeras

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P2093

A. N. Meyer

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B. D. Galvin

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D. J. Donoghue

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K. C. Hart

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M. K. Webster

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A novel form of fibroblast growth factor receptor 2. Alternative splicing of the third immunoglobulin-like domain confers ligand binding specificity

Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

Mutations in the fibroblast growth factor receptor 2 gene cause Crouzon syndrome

A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome

Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2

Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene

Related fibroblast growth factor receptor genes exist in the human genome

Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2)

Structural and functional diversity in the FGF receptor multigene family

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7894–7899

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scholarly article

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3850998

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10.1073/PNAS.93.15.7894

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15

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93

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1996-07-23T00:00:00Z

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14446242

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8755573

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38845

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