Cytochrome P450 oxidations in the generation of reactive electrophiles: epoxidation and related reactions
about
Reactive metabolites in the biotransformation of molecules containing a furan ringStructure of Cytochrome P450 PimD Suggests Epoxidation of the Polyene Macrolide Pimaricin Occurs via a Hydroperoxoferric IntermediateStructural basis for the 4'-hydroxylation of diclofenac by a microbial cytochrome P450 monooxygenaseEngineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediationWill 1,2-dihydro-1,2-azaborine-based drugs resist metabolism by cytochrome P450 compound I?Contributions of human enzymes in carcinogen metabolismMicrobial biotransformation of furosemide for environmental risk assessment: identification of metabolites and toxicological evaluation.Hydroxylated metabolites of 4-monochlorobiphenyl and its metabolic pathway in whole poplar plantsEpoxide formation on the aromatic B ring of flavanone by biphenyl dioxygenase of Pseudomonas pseudoalcaligenes KF707Identification of hydroxylated metabolites of 3,3',4,4'-tetrachlorobiphenyl and metabolic pathway in whole poplar plants.Enantioselective transport and biotransformation of chiral hydroxylated metabolites of polychlorinated biphenyls in whole poplar plants.Oxidative metabolism by P450 and function coupling to efflux systems: modulation of mycotoxin toxicity.Inhibition of cytochrome P450 1A2-mediated metabolism and production of reactive oxygen species by heme oxygenase-1 in rat liver microsomes.Differential repair of etheno-DNA adducts by bacterial and human AlkB proteinsNew hydroxylated metabolites of 4-monochlorobiphenyl in whole poplar plants.Cytochrome P450s and other enzymes in drug metabolism and toxicity.Differential subcellular distribution and colocalization of the microsomal and soluble epoxide hydrolases in cultured neonatal rat brain cortical astrocytesCafestol to Tricalysiolide B and Oxidized Analogues: Biosynthetic and Derivatization Studies Using Non-heme Iron Catalyst Fe(PDP).Inhibition of cytochromes P450 and the hydroxylation of 4-monochlorobiphenyl in whole poplarcis-Terpenones as an effective chemopreventive agent against aflatoxin B1-induced cytotoxicity and TCDD-induced P450 1A/B activity in HepG2 cells.Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties.Cytochromes P450: a structure-based summary of biotransformations using representative substrates.Identification and induction of cytochrome P450s involved in the metabolism of flavone-8-acetic acid in miceIn vitro evaluation of reversible and irreversible cytochrome P450 inhibition: current status on methodologies and their utility for predicting drug-drug interactions.Diversity of P450 enzymes in the biosynthesis of natural productsModeling Epoxidation of Drug-like Molecules with a Deep Machine Learning Network.DNA adduct formation by 7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes.Ring-oxidative biotransformation and drug interactions of propofol in the livers of rats.Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6.Antimalarial activity of a cis-terpenoneAn outbreak of canine aflatoxicosis in Gauteng Province, South Africa.Cytochrome P450/NADPH-dependent biosynthesis of 5,6-trans-epoxyeicosatrienoic acid from 5,6-trans-arachidonic acid.In vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys.Chemoenzymatic synthesis of monocyclic arene oxides and arene hydrates from substituted benzene substrates.Mass spectrometric studies of DNA adducts from a reaction with terpenoids.Cytochrome P450-catalysed arene-epoxidation of the bioactive tea tree oil ingredient p-cymene: indication for the formation of a reactive allergenic intermediate?Dunaliine A, a new amino diketone from Desmos dunalii (Annonaceae).Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung.Evidence for a complex formation between CYP2J5 and mEH in living cells by FRET analysis of membrane protein interaction in the endoplasmic reticulum (FAMPIR).Ethylene is oxidized to Ethylene oxide by CYP1A1
P2860
Q26860879-3BD8C73A-EE9B-4C0D-8C03-E6F021A199A4Q27664192-6E2915FF-359A-426C-9C29-1266C27C85EFQ27695727-31447959-0738-4B51-BDE2-E7519947C456Q28749176-242B3F07-4630-4D7A-80E0-E829E50FC42CQ28831263-0829FCAD-4996-4802-8E43-9F08D6D71BD5Q30520640-61A904BA-4081-4A4F-AD8B-9947CAD6DFD5Q31123434-D0BE3F63-50BC-45FB-B1C9-E5EE14E9456EQ33936000-816D14E7-E6B7-4BFD-8F68-C76F0DF1EBADQ33995859-40C01562-4916-4877-96D6-8A6EB762D583Q34143350-056DB5E7-54CC-4DA1-97C6-25D17A4719C7Q34394114-C0EF1F69-3DC6-49F5-AD27-A85FDA0FBBD4Q34434053-F4F4D7F5-4371-4FB2-A070-9D6623736F5CQ35656793-14F218DC-20C9-4BF6-B73D-CBB60091ADC9Q35673539-4911580A-8075-4B1B-BA80-A0B1C14ADD71Q35677375-7B7A71BA-70D1-4AEA-8F0E-31357365A09CQ36439150-93E8100D-25C5-4C2A-A6D0-A2A4340CF366Q36669750-970B8F37-B999-4B1B-A262-B28D10B81704Q36754666-80682065-5CB1-4FE2-AA51-C60383657922Q36840507-FF152027-5E44-4000-B661-ABC795796B57Q36857890-D0ED4A3E-52C8-4760-A2F7-F88EEC5656EEQ36906770-C85BE890-7F25-4DDD-A66E-1C411C4B5FD2Q37079954-188F0282-1027-4A02-81F6-C67FD791BBE1Q37096014-E82A4531-B931-4476-AFB8-2381C4F6923EQ37237438-32934A89-FB28-4141-86EC-F06AF9899B65Q38028349-CA2875D0-99E9-4CE7-B942-B5FF252F1726Q40028855-17068A3E-B4A0-4C81-804A-E0F227C73AFBQ40494075-561694A1-BE5D-41A9-AED7-EF3393D137A7Q41787188-AC9C4A25-3529-4FF7-B667-1E7583AA5E71Q41934777-47B090D5-B682-4426-8368-B3B84F062A2CQ41938100-8851584D-61EE-4097-BC92-BE0A3FDD1D3EQ42278409-DCD419F0-D9FB-48C6-810F-4D5DA42C8B3CQ42953885-3D5482E1-79C4-4414-A1E1-6021F3234E2BQ42978612-56670392-E30E-4409-AD6F-2F3B7A181EF6Q43559718-5256CB44-4F0F-4EBC-8D9E-418708848D4EQ45184180-22FEE71C-FAA1-4421-99F1-4CBA0AEB99DCQ45990594-6923F83C-D201-433E-BDC0-ADAD401E4F88Q46032701-41A1FCD3-5C08-43B7-97D2-DFC928B9A9E3Q46664617-AB88D6D6-8897-4DD2-BF33-90F65267D201Q47654703-19BC962B-FF3E-4352-9696-56E5FC33A67EQ50295269-48FC7292-91A5-4C31-AD36-4D22A0FC6672
P2860
Cytochrome P450 oxidations in the generation of reactive electrophiles: epoxidation and related reactions
description
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Januar 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/01/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/01/01)
@nl
наукова стаття, опублікована в січні 2003
@uk
مقالة علمية (نشرت عام 2003)
@ar
name
Cytochrome P450 oxidations in ...... xidation and related reactions
@ast
Cytochrome P450 oxidations in ...... xidation and related reactions
@en
Cytochrome P450 oxidations in ...... xidation and related reactions
@nl
type
label
Cytochrome P450 oxidations in ...... xidation and related reactions
@ast
Cytochrome P450 oxidations in ...... xidation and related reactions
@en
Cytochrome P450 oxidations in ...... xidation and related reactions
@nl
prefLabel
Cytochrome P450 oxidations in ...... xidation and related reactions
@ast
Cytochrome P450 oxidations in ...... xidation and related reactions
@en
Cytochrome P450 oxidations in ...... xidation and related reactions
@nl
P3181
P1476
Cytochrome P450 oxidations in ...... xidation and related reactions
@en
P2093
F. Peter Guengerich
P3181
P356
10.1016/S0003-9861(02)00415-0
P407
P577
2003-01-01T00:00:00Z