Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
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Versatile biocatalysis of fungal cytochrome P450 monooxygenasesOptimization of the bacterial cytochrome P450 BM3 system for the production of human drug metabolitesInsights into regioselective metabolism of mefenamic acid by cytochrome P450 BM3 mutants through crystallography, docking, molecular dynamics, and free energy calculationsUse of chemical auxiliaries to control p450 enzymes for predictable oxidations at unactivated C-h bonds of substratesNon-natural olefin cyclopropanation catalyzed by diverse cytochrome P450s and other hemoproteins.Cytochrome P450: taming a wild type enzymeMonocrotophos induces the expression and activity of xenobiotic metabolizing enzymes in pre-sensitized cultured human brain cells.Application of a cocktail approach to screen cytochrome P450 BM3 libraries for metabolic activity and diversity.Development of NanoART for HIV Treatment: Minding the Cytochrome P450 (CYP) EnzymesRational engineering of the fungal P450 monooxygenase CYP5136A3 to improve its oxidizing activity toward polycyclic aromatic hydrocarbonsControlling substrate specificity and product regio- and stereo-selectivities of P450 enzymes without mutagenesis.P450(BM3) (CYP102A1): connecting the dots.Potential applications of bioprocess technology in petroleum industry.The evolution of our understanding of endo-xenobiotic crosstalk and cytochrome P450 regulation and the therapeutic implications.Cytochrome P450-Mediated Phytoremediation using Transgenic Plants: A Need for Engineered Cytochrome P450 Enzymes.Enzymatic Assays Coupled with Mass Spectrometry with or without Embedded Liquid Chromatography.Enzyme/Prodrug Systems for Cancer Gene Therapy.Biomolecular engineering for nanobio/bionanotechnology.Type II ligands as chemical auxiliaries to favor enzymatic transformations by P450 2E1.Pyran formation by an atypical CYP-mediated four-electron oxygenation-cyclization cascade in an engineered aureothin pathway.Aldehyde and Ketone Synthesis by P450-Catalyzed Oxidative Deamination of Alkyl Azides.Challenges and Opportunities of Cytochrome P450-Mediated Phytoremediation.Analysis of Cytochrome P450 Conserved Sequence Motifs between Helices E and H: Prediction of Critical Motifs and Residues in Enzyme Functions.Engineering of human CYP3A enzymes by combination of activating polymorphic variants.Screening for cytochrome P450 expression in Pichia pastoris whole cells by P450-carbon monoxide complex determination.Specific packaging and circulation of cytochromes P450, especially 2E1 isozyme, in human plasma exosomes and their implications in cellular communications.As a painkiller: a review of pre- and postnatal non-steroidal anti-inflammatory drug exposure effects on the nervous systems.Oxygenation cascade analysis in conversion of n-octane catalyzed by cytochrome P450 CYP102A3 mutants at the P331 site.Laboratory-Scale Hydroxylation of Steroids by P450BM3 Variants.Degrading Organic Micropollutants: The Next Challenge in the Evolution of Biological Wastewater Treatment ProcessesCytochromes P450 as useful biocatalysts: addressing the limitations
P2860
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P2860
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@ast
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@en
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@nl
type
label
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@ast
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@en
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@nl
prefLabel
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@ast
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@en
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@nl
P2860
P3181
P1476
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
@en
P2093
Santosh Kumar
P2860
P304
P3181
P356
10.1517/17425250903431040
P407
P577
2010-02-01T00:00:00Z