Proteolytic activation of human factors IX and X by recombinant human factor VIIa: effects of calcium, phospholipids, and tissue factor
about
Crystal structure of Mg2+- and Ca2+-bound Gla domain of factor IX complexed with binding proteinMechanism of the Ca2+-induced Enhancement of the Intrinsic Factor VIIa ActivityX-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognitionCarbohydrates and activity of natural and recombinant tissue factorBiology of tissue factor pathway inhibitor.Systems biology of coagulation initiation: kinetics of thrombin generation in resting and activated human blood.Carboxypeptidase U at the interface between coagulation and fibrinolysis.Hepsin, a putative membrane-associated serine protease, activates human factor VII and initiates a pathway of blood coagulation on the cell surface leading to thrombin formation.The tissue factor requirement in blood coagulation.Role of tissue factor in thrombosis in antiphospholipid antibody syndrome.Role of tissue factor in venous thrombosis.Molecular intercommunication between the complement and coagulation systemsBlood coagulation dynamics in haemostasis.Decryption of tissue factor.Thrombin activity propagates in space during blood coagulation as an excitation wave.How it all starts: Initiation of the clotting cascade.The hemostasis system in murine atherosclerosis.Measuring the mechanical properties of blood clots formed via the tissue factor pathway of coagulation.Tissue factor structure and function.Thrombin generation in hemorrhage control and vascular occlusion.Comparison of natural and recombinant tissue factor proteins: new insights.Characterization of transcriptional regulatory elements in the promoter region of the murine blood coagulation factor VII gene.The nature of the stable blood clot procoagulant activities.Factor VII mutant V154G models a zymogen-like form of factor VIIa.Influence of mutations in tissue factor on the fine specificity of macromolecular substrate activation.Use of annexin-V to demonstrate the role of phosphatidylserine exposure in the maintenance of haemostatic balance by endothelial cells.Factor VIIa modified in the 170 loop shows enhanced catalytic activity but does not change the zymogen-like property.Role of the Gla and first epidermal growth factor-like domains of factor X in the prothrombinase and tissue factor-factor VIIa complexes.Prerequisites for recombinant factor VIIa-induced thrombin generation in plasmas deficient in factors VIII, IX or XI.Can the diagnostic reliability of the thrombin generation test as a global haemostasis assay be improved? The impact of calcium chloride concentration.Clinical pharmacological study of a plasma-derived factor VIIa and factor X mixture (MC710) in haemophilia patients with inhibitors--phase I trial.Recombinant human factor VIIa (rFVIIa) in hemophilia: mode of action and evidence to date.factor X -> factor Xa + factor X activation peptide (TF:F7a catalyst)factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst)Formation of factors IXa and Xa by the extrinsic pathway: differential regulation by tissue factor pathway inhibitor and antithrombin III.The insect salivary protein, prolixin-S, inhibits factor IXa generation and Xase complex formation in the blood coagulation pathway.
P2860
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P2860
Proteolytic activation of human factors IX and X by recombinant human factor VIIa: effects of calcium, phospholipids, and tissue factor
description
1990 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1990 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1990
@ast
im Oktober 1990 veröffentlicher wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 1990/10/09)
@sk
vědecký článek publikovaný v roce 1990
@cs
wetenschappelijk artikel (gepubliceerd op 1990/10/09)
@nl
наукова стаття, опублікована в жовтні 1990
@uk
مقالة علمية (نشرت في 9-10-1990)
@ar
name
Proteolytic activation of huma ...... ospholipids, and tissue factor
@ast
Proteolytic activation of huma ...... ospholipids, and tissue factor
@en
Proteolytic activation of huma ...... ospholipids, and tissue factor
@nl
type
label
Proteolytic activation of huma ...... ospholipids, and tissue factor
@ast
Proteolytic activation of huma ...... ospholipids, and tissue factor
@en
Proteolytic activation of huma ...... ospholipids, and tissue factor
@nl
prefLabel
Proteolytic activation of huma ...... ospholipids, and tissue factor
@ast
Proteolytic activation of huma ...... ospholipids, and tissue factor
@en
Proteolytic activation of huma ...... ospholipids, and tissue factor
@nl
P2093
P356
P1433
P1476
Proteolytic activation of huma ...... ospholipids, and tissue factor
@en
P2093
A. H. Pedersen
Y. Komiyama
P304
P356
10.1021/BI00492A016
P407
P577
1990-10-09T00:00:00Z