Activation of factor VIII by thrombin increases its affinity for binding to synthetic phospholipid membranes and activated platelets

Activation of factor VIII by thrombin increases its affinity for binding to synthetic phospholipid membranes and activated platelets

Item
http://www.wikidata.org/entity/Q28631517
Crystal structure of the bovine lactadherin C2 domain, a membrane binding motif, shows similarity to the C2 domains of factor V and factor VIIIA3 domain region 1803-1818 contributes to the stability of activated factor VIII and includes a binding site for activated factor IXThe factor VIII C1 domain contributes to platelet bindingPhosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a miceSoy phosphatidylinositol containing nanoparticle prolongs hemostatic activity of B-domain deleted factor VIII in hemophilia A mice.Immunogenicity and pharmacokinetic studies of recombinant factor VIII containing lipid cochleates.Biophysical characterization of anticoagulant hemextin AB complex from the venom of snake Hemachatus haemachatus.Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.Membrane-binding properties of the Factor VIII C2 domain.O-phospho-L-serine, multi-functional excipient for B domain deleted recombinant factor VIII.Role of glycosylation in conformational stability, activity, macromolecular interaction and immunogenicity of recombinant human factor VIIIBlood Clotting Factor VIII: From Evolution to Therapy.Interaction of the 268-282 region of glycoprotein Ibalpha with the heparin-binding site of thrombin inhibits the enzyme activation of factor VIII.Stabilizing interactions between D666-S1787 and T657-Y1792 at the A2-A3 interface support factor VIIIa stability in the blood clotting pathway.Platelet binding sites for factor VIII in relation to fibrin and phosphatidylserine.Kinetics of Factor X activation by the membrane-bound complex of Factor IXa and Factor VIIIa.factor VIIIa associates with cell membrane
P2860

Activation of factor VIII by thrombin increases its affinity for binding to synthetic phospholipid membranes and activated platelets

Item
http://www.wikidata.org/entity/Q28631517
description
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1998
@ast
im Oktober 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/10/23)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/10/23)
@nl
наукова стаття, опублікована в жовтні 1998
@uk
name
Activation of factor VIII by t ...... branes and activated platelets
@ast
Activation of factor VIII by t ...... branes and activated platelets
@en
Activation of factor VIII by t ...... branes and activated platelets
@nl
type
label
Activation of factor VIII by t ...... branes and activated platelets
@ast
Activation of factor VIII by t ...... branes and activated platelets
@en
Activation of factor VIII by t ...... branes and activated platelets
@nl
prefLabel
Activation of factor VIII by t ...... branes and activated platelets
@ast
Activation of factor VIII by t ...... branes and activated platelets
@en
Activation of factor VIII by t ...... branes and activated platelets
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Activation of factor VIII by t ...... branes and activated platelets
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698