Phosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a mice

Phosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a mice

Item
http://www.wikidata.org/entity/Q33954639
Effects of replacement of factor VIII amino acids Asp519 and Glu665 with Val on plasma survival and efficacy in vivo.Soy phosphatidylinositol containing nanoparticle prolongs hemostatic activity of B-domain deleted factor VIII in hemophilia A mice.Targeting liposomes loaded with melphalan prodrug to tumour vasculature via the Sialyl Lewis X selectin ligand.Phosphatidylinositol induces fluid phase formation and packing defects in phosphatidylcholine model membranesPEGylation of a factor VIII-phosphatidylinositol complex: pharmacokinetics and immunogenicity in hemophilia A mice.A novel ovine ex vivo arteriovenous shunt model to test vascular implantability.Allometry of factor VIII and informed scaling of next-generation therapeutic proteins.Native-like aggregates of factor VIII are immunogenic in von Willebrand factor deficient and hemophilia a miceNonlinear pharmacokinetics of factor VIII and its phosphatidylinositol lipidic complex in hemophilia A mice.Downregulation of CD40 signal and induction of TGF-β by phosphatidylinositol mediates reduction in immunogenicity against recombinant human Factor VIIIGenetic risk factors for inhibitors in haemophilia A.Factor VIII associated with lipidic nanoparticles retains efficacy in the presence of anti-factor VIII antibodies in hemophilia A mice.Soy Phosphatidylinositol-Containing Lipid Nanoparticle Prolongs the Plasma Survival and Hemostatic Efficacy of B-domain-Deleted Recombinant Canine Factor VIII in Hemophilia A Dogs.An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia.
P2860

Phosphatidylinositol containing lipidic particles reduces immunogenicity and catabolism of factor VIII in hemophilia a mice

Item
http://www.wikidata.org/entity/Q33954639
description
2010 nî lūn-bûn
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2010 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Phosphatidylinositol containin ...... ctor VIII in hemophilia a mice
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Phosphatidylinositol containin ...... ctor VIII in hemophilia a mice
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type
label
Phosphatidylinositol containin ...... ctor VIII in hemophilia a mice
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Phosphatidylinositol containin ...... ctor VIII in hemophilia a mice
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prefLabel
Phosphatidylinositol containin ...... ctor VIII in hemophilia a mice
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Phosphatidylinositol containin ...... ctor VIII in hemophilia a mice
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P1433
P1476
P2093
P2860
P2888
P304
P31
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P433
P478
P577
P5875
P6179
P698
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P1476
Phosphatidylinositol containin ...... ctor VIII in hemophilia a mice
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P577
P5875
P6179
P698
P921
P932