The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
about
Fluoride complexes of aluminium or beryllium act on G-proteins as reversibly bound analogues of the gamma phosphate of GTPThe GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunitsSignal activation and inactivation by the Gα helical domain: a long-neglected partner in G protein signalingHelix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in Gα i Subunits † , ‡Coactivation of G protein signaling by cell-surface receptors and an intracellular exchange factorA point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamicsThe mechanism of inhibition of Ran-dependent nuclear transport by cellular ATP depletion.Structure of Galpha(i1) bound to a GDP-selective peptide provides insight into guanine nucleotide exchangeTwo Galpha(i1) rate-modifying mutations act in concert to allow receptor-independent, steady-state measurements of RGS protein activityA bacterial Ras-like small GTP-binding protein and its cognate GAP establish a dynamic spatial polarity axis to control directed motility.Molecular mechanisms of go signalingBinding of GTPgamma[35S] is regulated by GDP and receptor activation. Studies with the nociceptin/orphanin FQ receptor.Mutant G protein alpha subunit activated by Gbeta gamma: a model for receptor activation?A model of the muscarinic receptor-induced changes in K(+)-current and action potentials in the bullfrog atrial cell.Signal sequence recognition and targeting of ribosomes to the endoplasmic reticulum by the signal recognition particle do not require GTP.Determination of absolute amounts of GDP and GTP bound to Ras in mammalian cells: comparison of parental and Ras-overproducing NIH 3T3 fibroblastsA dominant-negative Galpha mutant that traps a stable rhodopsin-Galpha-GTP-betagamma complex.A Gsalpha mutant designed to inhibit receptor signaling through Gs.A mutation in the heterotrimeric stimulatory guanine nucleotide binding protein alpha-subunit with impaired receptor-mediated activation because of elevated GTPase activity.The basic secretagogue compound 48/80 activates G proteins indirectly via stimulation of phospholipase D-lysophosphatidic acid receptor axis and 5-HT1A receptors in rat brain sections.GTPase acceleration as the rate-limiting step in Arabidopsis G protein-coupled sugar signaling.Drug Target Exploitable Structural Features of Adenylyl Cyclase Activity in Schistosoma mansoniThe nature and origin of spontaneous noise in G protein-gated ion channels.The same mutation in Gsalpha and transducin alpha reveals behavioral differences between these highly homologous G protein alpha-subunits.State-selective binding peptides for heterotrimeric G-protein subunits: novel tools for investigating G-protein signaling dynamics.Increased Gsα within blood cell membrane lipid microdomains in some depressive disorders: an exploratory study.Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide.Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease.Eukaryotic G protein signaling evolved to require G protein-coupled receptors for activation.A sweet cycle for Arabidopsis G-proteins: Recent discoveries and controversies in plant G-protein signal transductionMembrane fusion protein synexin (annexin VII) as a Ca2+/GTP sensor in exocytotic secretion.The arflike gene encodes an essential GTP-binding protein in Drosophila.Application of Hybrid Functional Groups to Predict ATP Binding Proteins.Invited review: Activation of G proteins by GTP and the mechanism of Gα-catalyzed GTP hydrolysis.Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).YFa and analogs: investigation of opioid receptors in smooth muscle contraction.Biochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A.The inhibition of the GTPase activating protein-Ha-ras interaction by acidic lipids is due to physical association of the C-terminal domain of the GTPase activating protein with micellar structures.Integration of Fourier Transform Infrared Spectroscopy, Fluorescence Spectroscopy, Steady-state Kinetics and Molecular Dynamics Simulations of Gαi1 Distinguishes between the GTP Hydrolysis and GDP Release Mechanism.Palmitoylation alters protein activity: blockade of G(o) stimulation by GAP-43.
P2860
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P2860
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
description
1986 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1986
@ast
im Juni 1986 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1986/06/05)
@sk
vědecký článek publikovaný v roce 1986
@cs
wetenschappelijk artikel (gepubliceerd op 1986/06/05)
@nl
наукова стаття, опублікована в червні 1986
@uk
name
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@ast
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@en
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@nl
type
label
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@ast
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@en
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@nl
prefLabel
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@ast
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@en
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@nl
P2093
P1476
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins
@en
P2093
A. G. Gilman
K. M. Ferguson
M. D. Smigel
T. Higashijima
P304
P407
P577
1986-06-05T00:00:00Z