Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide.
about
R-Ras3/M-Ras induces neuronal differentiation of PC12 cells through cell-type-specific activation of the mitogen-activated protein kinase cascade.Identification of a nucleotide exchange-promoting activity for p21ras.Control of growth and squamous differentiation in normal human bronchial epithelial cells by chemical and biological modifiers and transferred genes.A gene which encodes a predicted protein kinase can restore some functions of the ras gene in fission yeast.Expression of the Aplysia californica rho gene in Escherichia coli: purification and characterization of its encoded p21 productTwo types of RAS mutants that dominantly interfere with activators of RAS.Induction of differentiation in v-Ha-ras-transformed MDCK cells by prostaglandin E2 and 8-bromo-cyclic AMP is associated with a decrease in steady-state level of inositol 1,4,5-trisphosphateH-ras mutants lacking the epitope for the neutralizing monoclonal antibody Y13-259 show decreased biological activity and are deficient in GTPase-activating protein interaction.Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins.Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.Characterization of a factor that stimulates hydrolysis of GTP bound to ras gene product p21 (GTPase-activating protein) and correlation of its activity to cell densityStructural significance of the GTP-binding domain of ras p21 studied by site-directed mutagenesisOncogenic proteins new targets for chemotherapeutic agents against cancer.Concurrent mutations in two different ras genes in acute myelocytic leukemias.A dominant activating mutation in the effector region of RAS abolishes IRA2 sensitivity.Conformational alterations detected by circular dichroism induced in the normal ras p21 protein by activating point mutations at position 12, 59, or 61.Interactions of the ras-like protein p25rab3A with Mg2+ and guanine nucleotides.Interaction of a novel fluorescent GTP analogue with the small G-protein K-Ras.Co-regulation of metastatic and transforming activity of normal and mutant ras genes.v-Ha-Ras insertion/deletion mutants with reduced protease-inhibitory activity have no transforming activity.Modified responsiveness of v-Ha-ras-transfected rat fibroblasts to growth factors and a tumor promoter.
P2860
Q24537710-72E409A7-2852-4E27-A3EA-0B6C1D2E44C9Q33731473-A176BEE6-1D71-42D8-8BD8-6DB4D4139453Q35032913-FD75CA4C-F16B-4AEC-A609-F882DB36BA8CQ35980184-F9872745-3B6D-4296-9DC9-30EAB342F787Q36432557-120F6E3B-7ADC-432A-8539-A28FDA7B0CE5Q36654269-915F468F-2A9E-4252-9A27-8B7182041DF5Q36713007-88B7CB97-81F2-4354-8EB5-E2FFD4763C5BQ36764667-E70A47E1-2821-4F18-B4A1-683EC87D844FQ36790397-25C6C1B2-4895-44D6-AE1A-869E00BB9DBFQ36792845-0C08D242-B4C0-4851-B645-674642CCE6D9Q36846671-4DD0F90C-A3BA-44F5-ACA1-CAAD0753F978Q36920659-81887FA5-04B2-43C0-9A22-5BCBAB399CBDQ37859662-23FA01FB-F13E-4697-85AB-7C9E89BC2589Q40389164-B76FD951-F641-45E2-9DD8-6F5A57B6D8BEQ40653993-3A0919FE-7FF3-4300-98A0-710BEA616BF6Q41429329-9C3542C5-E9E4-441A-A5CE-6C38AC320D4EQ42118128-9ECF75EC-226D-42C0-B7A6-B5B1CB63CF85Q42571357-1323F56F-9D06-4F6F-9E49-3226501F3EDCQ42799422-555BD4B8-7923-40C8-9D8E-B9902A49D017Q42811099-B636D90F-1E04-462B-8978-4B76007D7D18Q53524998-050B0B37-AADA-46D2-B689-29EA91C44378
P2860
Activation of ras p21 transforming properties associated with an increase in the release rate of bound guanine nucleotide.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Activation of ras p21 transfor ...... e of bound guanine nucleotide.
@en
type
label
Activation of ras p21 transfor ...... e of bound guanine nucleotide.
@en
prefLabel
Activation of ras p21 transfor ...... e of bound guanine nucleotide.
@en
P2860
P356
P1476
Activation of ras p21 transfor ...... e of bound guanine nucleotide.
@en
P2093
P2860
P304
P356
10.1128/MCB.6.12.4214
P407
P577
1986-12-01T00:00:00Z