The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase
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Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNARNase H activity: structure, specificity, and function in reverse transcriptionRibonuclease H: properties, substrate specificity and roles in retroviral reverse transcriptionHIV-1 reverse transcriptionStructural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybridCoordination between the polymerase and RNase H activity of HIV-1 reverse transcriptaseEffect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity.Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5' plus-strand DNA ends in vivo.Alternate polypurine tracts (PPTs) affect the rous sarcoma virus RNase H cleavage specificity and reveal a preferential cleavage following a GA dinucleotide sequence at the PPT-U3 junction.Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions.A ribose sugar conformational switch in the LTR-retrotransposon Ty3 polypurine tract-containing RNA/DNA hybrid.Viral reverse transcriptases show selective high affinity binding to DNA-DNA primer-templates that resemble the polypurine tract.Specific cleavages by RNase H facilitate initiation of plus-strand RNA synthesis by Moloney murine leukemia virus.SiRNA-induced mutation in HIV-1 polypurine tract region and its influence on viral fitness.Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis.Sequence and structural determinants required for priming of plus-strand DNA synthesis by the human immunodeficiency virus type 1 polypurine tract.Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection.Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free systemExtensive purifying selection acting on synonymous sites in HIV-1 Group M sequences.Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3' polypurine tract.Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavageInsights into the structure and activity of prototype foamy virus RNase H.Identification of a sequence element immediately upstream of the polypurine tract that is essential for replication of simian immunodeficiency virus.Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase.RNase H-mediated cleavage of the template strandRNase H-mediated degradation of the template strand3' PPT-primed initiation of plus-strand DNA synthesisEvaluation and prediction of the HIV-1 central polypurine tract influence on foamy viral vectors to transduce dividing and growth-arrested cells.
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P2860
The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase
description
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1993
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im März 1993 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1993/03/25)
@sk
vědecký článek publikovaný v roce 1993
@cs
wetenschappelijk artikel (gepubliceerd op 1993/03/25)
@nl
наукова стаття, опублікована в березні 1993
@uk
name
The sequence features importan ...... s type 1 reverse transcriptase
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The sequence features importan ...... s type 1 reverse transcriptase
@en
The sequence features importan ...... s type 1 reverse transcriptase
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type
label
The sequence features importan ...... s type 1 reverse transcriptase
@ast
The sequence features importan ...... s type 1 reverse transcriptase
@en
The sequence features importan ...... s type 1 reverse transcriptase
@nl
prefLabel
The sequence features importan ...... s type 1 reverse transcriptase
@ast
The sequence features importan ...... s type 1 reverse transcriptase
@en
The sequence features importan ...... s type 1 reverse transcriptase
@nl
P2093
P1476
The sequence features importan ...... s type 1 reverse transcriptase
@en
P2093
A. J. Rattray
J. J. Champoux
K. A. Pullen
P304
P407
P577
1993-03-25T00:00:00Z