Sequence and structural determinants required for priming of plus-strand DNA synthesis by the human immunodeficiency virus type 1 polypurine tract.
about
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNARNase H activity: structure, specificity, and function in reverse transcriptionRibonuclease H: properties, substrate specificity and roles in retroviral reverse transcriptionEffects of 3' untranslated region mutations on plus-strand priming during moloney murine leukemia virus replication.Actinomycin D inhibits human immunodeficiency virus type 1 minus-strand transfer in in vitro and endogenous reverse transcriptase assays.Effect of polypurine tract (PPT) mutations on human immunodeficiency virus type 1 replication: a virus with a completely randomized PPT retains low infectivity.Deletion of a short, untranslated region adjacent to the polypurine tract in Moloney murine leukemia virus leads to formation of aberrant 5' plus-strand DNA ends in vivo.Molecular requirements for human immunodeficiency virus type 1 plus-strand transfer: analysis in reconstituted and endogenous reverse transcription systems.Recent findings on the mechanisms involved in tenofovir resistance.Human immunodeficiency virus type 1 central DNA flap: dynamic terminal product of plus-strand displacement dna synthesis catalyzed by reverse transcriptase assisted by nucleocapsid protein.Alternate polypurine tracts (PPTs) affect the rous sarcoma virus RNase H cleavage specificity and reveal a preferential cleavage following a GA dinucleotide sequence at the PPT-U3 junction.Reverse transcriptase in motion: conformational dynamics of enzyme-substrate interactions.Mutations in the U5 sequences adjacent to the primer binding site do not affect tRNA cleavage by rous sarcoma virus RNase H but do cause aberrant integrations in vivoA ribose sugar conformational switch in the LTR-retrotransposon Ty3 polypurine tract-containing RNA/DNA hybrid.Sequence, distance, and accessibility are determinants of 5'-end-directed cleavages by retroviral RNases H.Viral reverse transcriptases show selective high affinity binding to DNA-DNA primer-templates that resemble the polypurine tract.Role of HIV-1 nucleocapsid protein in HIV-1 reverse transcription.Specific cleavages by RNase H facilitate initiation of plus-strand RNA synthesis by Moloney murine leukemia virus.Alternate polypurine tracts affect rous sarcoma virus integration in vivo.Human immunodeficiency virus type 2 reverse transcriptase activity in model systems that mimic steps in reverse transcription.SiRNA-induced mutation in HIV-1 polypurine tract region and its influence on viral fitness.Purine analog substitution of the HIV-1 polypurine tract primer defines regions controlling initiation of plus-strand DNA synthesis.Hydrolysis of RNA/DNA hybrids containing nonpolar pyrimidine isosteres defines regions essential for HIV type 1 polypurine tract selection.Deaminase-independent inhibition of HIV-1 reverse transcription by APOBEC3G.Mutations in the 5' end of the human immunodeficiency virus type 1 polypurine tract affect RNase H cleavage specificity and virus titer.Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free systemStructural probing of the HIV-1 polypurine tract RNA:DNA hybrid using classic nucleic acid ligands.Integration of rous sarcoma virus DNA: a CA dinucleotide is not required for integration of the U3 end of viral DNA.A new role for HIV nucleocapsid protein in modulating the specificity of plus strand priming.Fidelity of plus-strand priming requires the nucleic acid chaperone activity of HIV-1 nucleocapsid protein.Extensive purifying selection acting on synonymous sites in HIV-1 Group M sequences.Using pyrrolo-deoxycytosine to probe RNA/DNA hybrids containing the human immunodeficiency virus type-1 3' polypurine tract.Effects of mutations in the G tract of the human immunodeficiency virus type 1 polypurine tract on virus replication and RNase H cleavageSelection of optimal polypurine tract region sequences during Moloney murine leukemia virus replication.Identification of a central DNA flap in feline immunodeficiency virus.Identification of a sequence element immediately upstream of the polypurine tract that is essential for replication of simian immunodeficiency virus.Mechanism of polypurine tract primer generation by HIV-1 reverse transcriptase.
P2860
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P2860
Sequence and structural determinants required for priming of plus-strand DNA synthesis by the human immunodeficiency virus type 1 polypurine tract.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Sequence and structural determ ...... virus type 1 polypurine tract.
@ast
Sequence and structural determ ...... virus type 1 polypurine tract.
@en
type
label
Sequence and structural determ ...... virus type 1 polypurine tract.
@ast
Sequence and structural determ ...... virus type 1 polypurine tract.
@en
prefLabel
Sequence and structural determ ...... virus type 1 polypurine tract.
@ast
Sequence and structural determ ...... virus type 1 polypurine tract.
@en
P2860
P1433
P1476
Sequence and structural determ ...... virus type 1 polypurine tract
@en
P2093
P2860
P304
P407
P577
1996-08-01T00:00:00Z