Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy
about
Dynamic Viral Glycoprotein Machines: Approaches for Probing Transient States That Drive Membrane FusionThe HIV glycan shield as a target for broadly neutralizing antibodiesAntigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cellsTargeting host-derived glycans on enveloped viruses for antibody-based vaccine designAntibody potency relates to the ability to recognize the closed, pre-fusion form of HIV EnvStructural Constraints Determine the Glycosylation of HIV-1 Envelope TrimersGlycan clustering stabilizes the mannose patch of HIV-1 and preserves vulnerability to broadly neutralizing antibodiesVaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman PrimatesStable, uncleaved HIV-1 envelope glycoprotein gp140 forms a tightly folded trimer with a native-like structure.Crystal structure of the HIV neutralizing antibody 2G12 in complex with a bacterial oligosaccharide analog of mammalian oligomannoseEffects of the I559P gp41 change on the conformation and function of the human immunodeficiency virus (HIV-1) membrane envelope glycoprotein trimer.Functional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFLA New Approach to Produce HIV-1 Envelope Trimers: BOTH CLEAVAGE AND PROPER GLYCOSYLATION ARE ESSENTIAL TO GENERATE AUTHENTIC TRIMERSDesign and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens.Antibody recognition of HIV and dengue glycoproteins.Insights into the trimeric HIV-1 envelope glycoprotein structureChanges in Structure and Antigenicity of HIV-1 Env Trimers Resulting from Removal of a Conserved CD4 Binding Site-Proximal Glycan.Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design.Cleavage-independent HIV-1 Env trimers engineered as soluble native spike mimetics for vaccine design.Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.Glycan Microheterogeneity at the PGT135 Antibody Recognition Site on HIV-1 gp120 Reveals a Molecular Mechanism for Neutralization ResistanceRestricted HIV-1 Env Glycan Engagement by Lectin-Reengineered DAVEI Protein Chimera is sufficient for Lytic Inactivation of the Virus.Interrogation of side chain biases for oligomannose recognition by antibody 2G12 via structure-guided phage display libraries.CRISPR/Cas9 gene editing for the creation of an MGAT1-deficient CHO cell line to control HIV-1 vaccine glycosylation
P2860
Q26772129-AE1B31D8-D699-4958-BB74-48BF5653E898Q26786540-4573CED2-D407-4192-93D7-6D23568CC185Q27320687-16EA65AA-D38D-4B25-B0AB-F8B28352273EQ28084672-3B43F266-A139-43D7-BF6D-354E51CCDDF9Q28256508-7EA1CEA9-EA51-48BD-8197-598122CF4E22Q28263063-0240B9B8-A313-4DFF-BF64-78E7C4FBE620Q28263932-AC4083D8-638A-4F35-A63D-0FB262AAB80AQ33612459-3BBEE4B5-2806-4168-A1EA-910078601F12Q34831341-42C23FFD-3541-4792-AC5A-D762ECA3F4CBQ35119778-A2EBA326-41BA-49DD-953C-A0AB12E2C151Q35596474-38020AA5-F4D2-439C-AE2C-F66A00BC7560Q35913910-42E35352-41AA-4C02-9679-5A0225D9902DQ35925858-8E5893C3-8A2F-49BF-8FE8-EA96814F215EQ36102994-A42E6C28-A090-4DF0-9452-7FAFB4EC1270Q38293417-17B5E755-00D8-44BE-9FCF-09A4E402B10CQ38323609-08BA7558-3A09-4E65-B8D6-723B9261180DQ38753943-75FF08B5-D4C1-4BB9-A91A-BF1DBD145411Q40679052-93E4A545-E7A1-4AA0-992A-CA933E120F3FQ41042362-C55468FD-EE5E-46AF-8858-7E85BC3F0FF3Q41447893-EA9B13DF-66F7-48D4-BDDF-032B687E9D68Q42148324-00D33C45-EFC7-435D-AC52-8362696A7540Q47552223-5BC36977-2759-487B-9617-4C26EF053637Q47633687-60ADA0AB-DB93-4E35-BFDA-CDBADE44700DQ58693500-47FDFCDC-E863-489D-B164-926223D8099B
P2860
Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy
description
2014 nî lūn-bûn
@nan
2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@ast
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@en
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@nl
type
label
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@ast
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@en
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@nl
prefLabel
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@ast
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@en
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@nl
P2093
P2860
P356
P1433
P1476
Structure of 2G12 Fab2 in comp ...... e-particle electron microscopy
@en
P2093
Albert Cupo
Andrew B Ward
Charles D Murin
Dennis R Burton
John P Moore
Reza Khayat
Robyn L Stanfield
P2860
P304
P356
10.1128/JVI.01229-14
P407
P577
2014-09-01T00:00:00Z