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RNAi screening comes of age: improved techniques and complementary approaches

RNAi screening comes of age: improved techniques and complementary approaches

http://www.wikidata.org/entity/Q28654521

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Mapping paths: new approaches to dissect eukaryotic signaling circuitry Making Bunyaviruses Talk: Interrogation Tactics to Identify Host Factors Required for Infection Beyond editing: repurposing CRISPR-Cas9 for precision genome regulation and interrogation A new age in functional genomics using CRISPR/Cas9 in arrayed library screening High-throughput screening to enhance oncolytic virus immunotherapy Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference Electroporation Knows No Boundaries: The Use of Electrostimulation for siRNA Delivery in Cells and Tissues A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function.Decoding protein networks during virus entry by quantitative proteomics A Drosophila-centric view of protein tyrosine phosphatases Cell-Based Assay Design for High-Content Screening of Drug Candidates Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human Comparative chemical genomics reveal that the spiroindolone antimalarial KAE609 (Cipargamin) is a P-type ATPase inhibitor Positional RNA-Seq identifies candidate genes for phenotypic engineering of sexual traits.Reagent and Data Resources for Investigation of RNA Binding Protein Functions in Drosophila melanogaster Cultured Cells.Data Analysis for High-Throughput RNAi Screening.The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells Multiplex gene regulation by CRISPR-ddCpf1 CRISPR/Cas9: From Genome Engineering to Cancer Drug Discovery Choosing the Right Tool for the Job: RNAi, TALEN, or CRISPR.Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafish The environmental genomics of metazoan thermal adaptation.High-throughput functional genomics using CRISPR-Cas9.Functional genomic screening approaches in mechanistic toxicology and potential future applications of CRISPR-Cas9.Morphological Profiles of RNAi-Induced Gene Knockdown Are Highly Reproducible but Dominated by Seed Effects A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth Cellular Mechanisms of Drosophila Heart Morphogenesis.Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.The Power of Sophisticated Phenotypic Screening and Modern Mechanism-of-Action Methods.Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster.Outlier analysis of functional genomic profiles enriches for oncology targets and enables precision medicine.Design and Methods of Large-Scale RNA Interference Screens in Drosophila.A Guide to Genome-Wide In Vivo RNAi Applications in Drosophila.Nodes-and-connections RNAi knockdown screening: identification of a signaling molecule network involved in fulvestrant action and breast cancer prognosis.Reliance of Wolbachia on High Rates of Host Proteolysis Revealed by a Genome-Wide RNAi Screen of Drosophila Cells.Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi.Enhancer of polycomb coordinates multiple signaling pathways to promote both cyst and germline stem cell differentiation in the Drosophila adult testis.Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen Gene Perturbation Atlas (GPA): a single-gene perturbation repository for characterizing functional mechanisms of coding and non-coding genes In Vivo RNAi Screen Unveils PPARγ as a Regulator of Hematopoietic Stem Cell Homeostasis

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RNAi screening comes of age: improved techniques and complementary approaches

http://www.wikidata.org/entity/Q28654521

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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name

RNAi screening comes of age: improved techniques and complementary approaches

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RNAi screening comes of age: improved techniques and complementary approaches

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RNAi screening comes of age: improved techniques and complementary approaches

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type

label

RNAi screening comes of age: improved techniques and complementary approaches

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RNAi screening comes of age: improved techniques and complementary approaches

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RNAi screening comes of age: improved techniques and complementary approaches

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prefLabel

RNAi screening comes of age: improved techniques and complementary approaches

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RNAi screening comes of age: improved techniques and complementary approaches

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RNAi screening comes of age: improved techniques and complementary approaches

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Nature Reviews Molecular Cell Biology

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RNAi screening comes of age: improved techniques and complementary approaches

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P2093

Caroline E Shamu

http://www.w3.org/2001/XMLSchema#string

Jennifer A Smith

http://www.w3.org/2001/XMLSchema#string

Ralph A Neumüller

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A CRISPR CASe for high-throughput silencing

Identification of genes that promote or antagonize somatic homolog pairing using a high-throughput FISH-based screen

Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy

Secretion of Wnt ligands requires Evi, a conserved transmembrane protein

Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

Haploid genetic screens in human cells identify host factors used by pathogens

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.

Genomic screening with RNAi: results and challenges

Statistical methods for analysis of high-throughput RNA interference screens

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

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591-600

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835465

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10.1038/NRM3860

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9

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15

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Norbert Perrimon

Stephanie E Mohr

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2014-09-01T00:00:00Z

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1041566369

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25145850

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4204798

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